PIK3AP1 Antibody

中文名稱：

PIK3AP1兔多克隆抗體
貨號：

CSB-PA747806LA01HU
規格：

￥440
圖片：
Immunofluorescence staining of A549 cells with CSB-PA747806LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) PIK3AP1 Polyclonal antibody
Uniprot No.：

Q6ZUJ8
基因名：

PIK3AP1
別名：

PIK3AP1 antibody; BCAPPhosphoinositide 3-kinase adapter protein 1 antibody; B-cell adapter for phosphoinositide 3-kinase antibody; B-cell phosphoinositide 3-kinase adapter protein 1 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Phosphoinositide 3-kinase adapter protein 1 protein (293-404AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，PIK3AP1 Antibody (CSB-PA747806LA01HU)，的標記方式是Non-conjugated。對于PIK3AP1 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA747806LB01HU	PIK3AP1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA747806LC01HU	PIK3AP1 Antibody, FITC conjugated
Biotin	CSB-PA747806LD01HU	PIK3AP1 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IF

推薦稀釋比：

Application	Recommended Dilution
IF	1:50-1:200

Protocols：

ELISA Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Signaling adapter that contributes to B-cell development by linking B-cell receptor (BCR) signaling to the phosphoinositide 3-kinase (PI3K)-Akt signaling pathway. Has a complementary role to the BCR coreceptor CD19, coupling BCR and PI3K activation by providing a docking site for the PI3K subunit PIK3R1. Alternatively, links Toll-like receptor (TLR) signaling to PI3K activation, a process preventing excessive inflammatory cytokine production. Also involved in the activation of PI3K in natural killer cells. May be involved in the survival of mature B-cells via activation of REL.
基因功能參考文獻：
1. Dimeric BCAP associates with the TIR domains of TLR2/4 and MAL/TIRAP, suggesting that it is recruited to the TLR signalosome by multitypic TIR-TIR interactions. PMID: 27909057
2. Abi-1 promotes Abl-mediated BCAP phosphorylation and suggest that Abi-1 in general coordinates kinase-substrate interactions PMID: 15893754
亞細胞定位：

Cytoplasm. Cell membrane; Peripheral membrane protein.
組織特異性：

Expressed in natural killer (NK) cells.
數據庫鏈接：

HGNC: 30034

OMIM: 607942

KEGG: hsa:118788

STRING: 9606.ENSP00000339826

UniGene: Hs.310456

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