PGA3 Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) PGA3 Polyclonal antibody
Uniprot No.：

P0DJD8
基因名：

PGA3
別名：

PGA3 antibody; Pepsin A-3 antibody; EC 3.4.23.1 antibody; Pepsinogen-3 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Pepsin A-3 protein (16-388AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent.
基因功能參考文獻：
1. Low Pepsinogen I is associated with precancerous gastric lesions. PMID: 25292040
2. High serum Pepsinogen I level is associ9ated with the progression of gastric precancerous lesions. PMID: 24895149
3. Significantly higher AUC was observed for the PGI/PGII ratio and is associated with atrophy and intestinal metaplasia. PMID: 23886209
4. A significant negative correlation was found between the degree of corpus atrophy and the level of serum pepsinogen-I in atrophic gastritis patients with gastroesophageal reflux. PMID: 21175799
5. Higher levels of Pepsinogen I is associated with early gastric cancer PMID: 15688378
6. Helicobacter pylori eradication improves gastric histology and decreases serum gastrin, pepsinogen I and pepsinogen II levels in patients with duodenal ulcer. PMID: 17559360
7. pepsinogens may have a role in esophageal squamous dysplasia PMID: 18844222
8. Barrett's esophagus is characterized by the absence of Helicobacter pylori infection and high levels of serum pepsinogen I concentration in Japan. PMID: 19196398
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亞細胞定位：

Secreted.
蛋白家族：

Peptidase A1 family
數據庫鏈接：

HGNC: 8885

OMIM: 169700

KEGG: hsa:643834

STRING: 9606.ENSP00000322192

UniGene: Hs.601055

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