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中文名稱：PFKL兔多克隆抗體
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貨號：CSB-PA017821LA01HU
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規格：￥440
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圖片：
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Western Blot
Positive WB detected in: HepG2 whole cell lysate, HL60 whole cell lysate, Mouse liver tissue
All lanes: PFKL antibody at 2.8μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 86, 91 kDa
Observed band size: 86, 50, 40 kDa -
Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA017821LA01HU at dilution of 1:100 -
Immunofluorescent analysis of Hela cells using CSB-PA017821LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) PFKL Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：PFKL antibody; ATP-dependent 6-phosphofructokinase antibody; liver type antibody; ATP-PFK antibody; PFK-L antibody; EC 2.7.1.11 antibody; 6-phosphofructokinase type B antibody; Phosphofructo-1-kinase isozyme B antibody; PFK-B antibody; Phosphohexokinase antibody
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宿主：Rabbit
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反應種屬：Human, Mouse
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免疫原：Recombinant Human ATP-dependent 6-phosphofructokinase, liver type protein (229-479AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
本頁面中的產品，PFKL Antibody (CSB-PA017821LA01HU)，的標記方式是Non-conjugated。對于PFKL Antibody，我們還提供其他標記。見下表：
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA, WB, IHC, IF
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推薦稀釋比：
Application Recommended Dilution WB 1:1000-1:5000 IHC 1:20-1:200 IF 1:50-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
引用文獻
- Notch mediates the glycolytic switch via PI3K/Akt signaling to support embryonic development H Wang,Cellular & molecular biology letters,2023
產品評價
相關產品
靶點詳情
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功能：Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. Negatively regulates the phagocyte oxidative burst in response to bacterial infection by controlling cellular NADPH biosynthesis and NADPH oxidase-derived reactive oxygen species. Upon macrophage activation, drives the metabolic switch toward glycolysis, thus preventing glucose turnover that produces NADPH via pentose phosphate pathway.
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基因功能參考文獻：
- Liver PFK1 isoform assembles into filaments in a tetramer- and substrate-dependent manner,organizing isoform specific glucose metabolism in cells. PMID: 28646105
- findings showed glycosylation inhibited PFK1 activity and redirected glucose flux through the pentose phosphate pathway, thereby conferring a selective growth advantage on cancer cells PMID: 22923583
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亞細胞定位：Cytoplasm.
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蛋白家族：Phosphofructokinase type A (PFKA) family, ATP-dependent PFK group I subfamily, Eukaryotic two domain clade "E" sub-subfamily
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數據庫鏈接：
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