PEX14 Antibody
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中文名稱：PEX14兔多克隆抗體
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貨號(hào)：CSB-PA017800GA01HU
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規(guī)格：￥3,900
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：PEX14
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別名：dJ734G22.2 antibody; NAPP2 antibody; NF E2 associated polypeptide 2 antibody; Peroxin 14 antibody; Peroxin-14 antibody; Peroxisomal biogenesis factor 14 antibody; Peroxisomal membrane anchor protein PEX14 antibody; Peroxisomal membrane anchor protein Pex14p antibody; Peroxisomal membrane protein PEX14 antibody; pex14 antibody; PEX14_HUMAN antibody; Pex14p antibody; PTS1 receptor docking protein antibody; PTS1 receptor-docking protein antibody
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反應(yīng)種屬：Human,Mouse,Rat
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免疫原：Human PEX14
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20oC, Avoid freeze / thaw cycles.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,IF
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Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Peroxisome membrane protein that is an essential component of the peroxisomal import machinery. Functions as a docking factor for the predominantly cytoplasmic PTS1 receptor (PEX5). Plays a key role for peroxisome movement through a direct interaction with tubulin.
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基因功能參考文獻(xiàn)：
- data reveal subpopulations of peroxisomes showing only weak colocalization between PEX14 and PEX5 or PEX11 but at the same time a clear compartmentalized organization. This compartmentalization, which was less evident in cases of strong colocalization, indicates dynamic protein reorganization linked to changes occurring in the peroxisomes. PMID: 27311714
- PEX14 is the 13th PEX gene responsible for peroxisome biogenesis disorders. Thus far, only two patients with PEX14 deficiency have been reported. PMID: 26627464
- The novel Pex14-binding site may represent the initial tethering site of Pex5 from which the cargo-loaded receptor is further processed in a sequential manner. PMID: 24235149
- interaction of PEX5 with catalase and PEX14 PMID: 21976670
- PEX14 is a multi-tasking protein that not only facilitates peroxisomal protein import but is also required for peroxisome motility by serving as membrane anchor for microtubules. PMID: 21525035
- Serves as a transcriptional corepressor in addition to its peroxisomal function. PMID: 11863372
- peroxisomal localization of Pex14p is affected by Pex13p PMID: 14715663
- a new complementation group of the peroxisome biogenesis disorders with PEX14 as the defective gene PMID: 15146459
- This report represents the second PEX14-deficiency associated with Zellweger syndrome and the first documentation of a PEX14-deficient patient with detailed clinical follow-up and biochemical, morphological, and radiological data. PMID: 18285423
- N-terminal domain of Pex14, Pex14(N), adopts a three-helical fold. Pex5 and Pex19 ligand helices bind competitively to the same surface in Pex14(N) albeit with opposite directionality. PMID: 19197237
- analysis of the human Pex5.Pex14.PTS1 protein complex structure obtained by small angle X-ray scattering PMID: 19584060
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相關(guān)疾病：Peroxisome biogenesis disorder complementation group K (PBD-CGK); Peroxisome biogenesis disorder 13A (PBD13A)
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亞細(xì)胞定位：Peroxisome membrane; Peripheral membrane protein; Cytoplasmic side.
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蛋白家族：Peroxin-14 family
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數(shù)據(jù)庫(kù)鏈接：
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