PDCD2 Antibody
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中文名稱：PDCD2兔多克隆抗體
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貨號：CSB-PA558079
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規格：￥1100
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圖片：
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The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA558079(PDCD2 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200) -
The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using CSB-PA558079(PDCD2 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
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其他：
產品詳情
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Uniprot No.：
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基因名：PDCD2
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別名：MGC12347 antibody; OTTHUMP00000017702 antibody; PDCD 2 antibody; Pdcd2 antibody; PDCD2 protein antibody; PDCD2_HUMAN antibody; Programmed cell death 2 antibody; Programmed cell death protein 2 antibody; RP 8 antibody; RP8 antibody; Rp8 homolog antibody; Zinc finger MYND domain containing protein 7 antibody; Zinc finger MYND domain-containing protein 7 antibody; Zinc finger protein Rp 8 antibody; Zinc finger protein Rp-8 antibody; Zinc finger protein Rp8 antibody; ZMYND 7 antibody; ZMYND7 antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Synthetic peptide of Human PDCD2
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：Antigen affinity purification
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產品提供形式：Liquid
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應用范圍：ELISA,IHC
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推薦稀釋比：
Application Recommended Dilution ELISA 1:2000-1:10000 IHC 1:50-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：May be a DNA-binding protein with a regulatory function. May play an important role in cell death and/or in regulation of cell proliferation.
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基因功能參考文獻：
- PDCD2 and NCoR1 may act as tumor suppressors in Gastrointestinal stromal tumors cells through the Smad signaling pathway. PMID: 26589942
- PDCD2 may play an important role in tumor suppression in osteosarcoma. These mechanisms might be related to immune response induced by CD4(+) and CD8(+) T cells. PMID: 26617804
- Low PDCD2 expression is associated with gastric cancer. PMID: 25111461
- Loss of PDCD2 expression could contribute to gastric cancer development and progression. PMID: 25334010
- Expression of human PDCD2 fully rescues the Drosophila Zfrp8 phenotype, underlining the functional conservation of Zfrp8/PDCD2. PMID: 24381196
- PDCD2 RNA expression in acute leukemia patients correlates with disease status and is a significant predictor of clinical relapse. PMID: 23760497
- PDCD2 has a novel regulatory role in human hematopoiesis and is essential for erythroid development. PMID: 22922207
- Transfection of a construct expressing PDCD2 induces apoptosis in human cell lines through activation of the caspase cascade. PMID: 20605493
- To study the role of PDCD2_C domain in apoptosis, the cDNAs of two isoforms of PDCD2 and MGC13096 were cloned. PDCD2 (NM_002598) was over expressed when endothelial cells treated with leukotriene D4 or natural killer cells were activated by IL-2. PMID: 16311922
- repression of PDCD2 by BCL6 is likely important in the pathogenesis of certain human lymphomas PMID: 17468402
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亞細胞定位：Nucleus.
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組織特異性：Ubiquitous.
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數據庫鏈接：
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Species Reactivity: Human, Mouse, Rat
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