OVOL1 Antibody

說明書

中文名稱：

OVOL1兔多克隆抗體
貨號：

CSB-PA017303LA01HU
規(guī)格：

￥3,900
圖片：
Western Blot
Positive WB detected in: U251 whole cell lysate(20μg), MCF7 whole cell lysate(20μg), PC-3 whole cell lysate(20μg), 293T whole cell lysate(20μg), A549 whole cell lysate(20μg),Mouse Brain tissue lysate(20μg)
All lanes: OVOL1 antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 31 kDa
Observed band size: 31 kDa
Exposure time: 30s

IHC image of CSB-PA017303LA01HU diluted at 1:50 and staining in paraffin-embedded human stomach tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB. Secondary antibody only control: uses 1% BSA instead of primary antibody

IHC image of CSB-PA017303LA01HU diluted at 1:50 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB. Secondary antibody only control: uses 1% BSA instead of primary antibody
其他：

產品詳情
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靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) OVOL1 Polyclonal antibody
Uniprot No.：

O14753
基因名：

OVOL1
別名：

hOvo1 antibody; Ovo homolog like 1 antibody; Ovo like 1(Drosophila) antibody; Ovo, Drosophila, homolog-like, 1 antibody; Ovol1 antibody; OVOL1_HUMAN antibody; Putative transcription factor Ovo like 1 antibody; Putative transcription factor Ovo-like 1 antibody
宿主：

Rabbit
反應種屬：

Human, Mouse
免疫原：

Recombinant Human Putative transcription factor Ovo-like 1 protein (9-267AA)
免疫原種屬：

Homo sapiens (Human)
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen?affinity?purification
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.02% sodium azide
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB, IHC

推薦稀釋比：

Application	Recommended Dilution
WB	1:1000-1:3000
IHC	1:50-1:200

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Putative transcription factor. Involved in hair formation and spermatogenesis. May function in the differentiation and/or maintenance of the urogenital system.
基因功能參考文獻：
1. OVOL1 is an integral part of the aryl hydrocarbon receptor-mediated mechanism of Filaggrin expression in human keratinocytes. PMID: 28703805
2. that the OVOL1-OVOL2 axis may actively contribute to cell differentiation and proliferation in the hair bulb PMID: 26873447
3. OVOL1 is a regulator of trophoblast progenitor cell fate during human trophoblast development. PMID: 26504231
4. KIF3A and OVOL1 are involved in the development of Atopic dermatitis in the Chinese pediatric population. PMID: 26127003
5. OVOL1 may play an important role in human skin morphogenesis and tumorigenesis. PMID: 25509883
6. Association of KIF3A, but not OVOL1 and ACTL9, with atopic eczema in Italian patients PMID: 23278845
7. Molecular phylogeny of OVOL1, OVOL2 and OVOL3 genes illustrates a conserved C2H2 zinc finger domain coupled by hypervariable unstructured regions in humans and other species PMID: 22737237
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亞細胞定位：

Nucleus.
組織特異性：

Expressed in fetal kidney, and also in adult pancreas and placenta. Not expressed in intestine, peripheral blood lymphocytes and ovary.
數據庫鏈接：

HGNC: 8525

OMIM: 602313

KEGG: hsa:5017

STRING: 9606.ENSP00000337862

UniGene: Hs.134434

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