OLIG1 Antibody

中文名稱：

OLIG1兔多克隆抗體
貨號：

CSB-PA016328YA01HU
規格：

￥440
圖片：
Western Blot
Positive WB detected in: THP-1 whole cell lysate, Rat brain tissue, Rat lung tissue, Mouse spleen tissue, Mouse brain tissue
All lanes: OLIG1 antibody at 2.8µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 28 kDa
Observed band size: 28 kDa
其他：

產品詳情
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靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) OLIG1 Polyclonal antibody
Uniprot No.：

Q8TAK6
基因名：

OLIG1
別名：

Basic domain helix loop helix protein class B 6 antibody; Basic domain helix loop helix protein class B6 antibody; BHLH B6 antibody; BHLHB 6 antibody; bHLHb6 antibody; bHLHe21 antibody; Class B basic helix-loop-helix protein 6 antibody; Class E basic helix-loop-helix protein 21 antibody; Olig 1 antibody; Olig1 antibody; OLIG1_HUMAN antibody; Oligo 1 antibody; Oligo1 antibody; Oligodendrocyte lineage transcription factor 1 antibody; Oligodendrocyte specific bHLH transcription factor 1 antibody; Oligodendrocyte transcription factor 1 antibody
宿主：

Rabbit
反應種屬：

Human, Mouse, Rat
免疫原：

Recombinant Human Oligodendrocyte transcription factor 1 protein (17-105AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，OLIG1 Antibody (CSB-PA016328YA01HU)，的標記方式是Non-conjugated。對于OLIG1 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA016328YB01HU	OLIG1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA016328YC01HU	OLIG1 Antibody, FITC conjugated
Biotin	CSB-PA016328YD01HU	OLIG1 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:5000

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Promotes formation and maturation of oligodendrocytes, especially within the brain. Cooperates with OLIG2 to establish the pMN domain of the embryonic neural tube.
基因功能參考文獻：
1. Olig1 has a critical function in regulation of postnatal neural progenitor cell production in response to Noggin. PMID: 28253550
2. This study demonstrated that increased expression of mRNA of OLIG1 in ventral prefrontal white matter in major depressive disorder. PMID: 25930075
3. Olig1 is a Smad cofactor involved in TGF-beta-induced cell motility PMID: 23720758
4. This study review OLIG1 have developmental functions in patterning, neuron subtype specification and the formation of oligodendrocytes and play the role in the postnatal brain during repair processes and in neurological disease states. PMID: 23165259
5. Olig1 was not expressed in freshly isolated oligodendrocytes, but is expressed from the beginning of process extension until membrane maintenance. PMID: 21446039
6. analysis of conserved and non-conserved functional elements at the Olig1 and Olig2 locus PMID: 21206754
7. Olig1 and Olig2 transcription factors in the human central nervous system are important not only for differentiation of the oligodendrocyte lineage, but they may also have a role in neural cell specification. PMID: 16267213
8. identified novel coding variants in the Olig1 gene, including a trinucleotide repeat, but found no evidence to support the hypothesis that genetic variation in Olig1 influences susceptibility to multiple sclerosis PMID: 16820418
9. Mutations in OLIG1 and OLIG2 are not likely to be associated with this subgroup of hypomyelinating disorders. PMID: 17171653
10. OLIG1 protein expression significantly correlates with overall survival in non-small cell lung cancer patients PMID: 17388669
11. No significan correlation was found between proliferation index in pilocytic astrocytomas and Olig-1 expression. PMID: 17690840
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亞細胞定位：

Nucleus.
組織特異性：

Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas is highly variable.
數據庫鏈接：

HGNC: 16983

OMIM: 606385

KEGG: hsa:116448

STRING: 9606.ENSP00000371785

UniGene: Hs.56663

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