OAZ3 Antibody, FITC conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) OAZ3 Polyclonal antibody
Uniprot No.：

Q9UMX2
基因名：

OAZ3
別名：

Antizyme 3 antibody; AZ3 antibody; OAZ t antibody; OAZ3 antibody; OAZ3_HUMAN antibody; ODC-Az 3 antibody; Ornithine decarboxylase antizyme 3 antibody; RP11-98D18.13-004 antibody; Testicular secretory protein Li 31 antibody; TISP15 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Ornithine decarboxylase antizyme 3 protein (1-190AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

FITC
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimers. Does not target the ODC monomers for degradation, which allows a protein synthesis-independent restoration of ODC activity. Stabilizes AZIN2 by interfering with its ubiquitination. Involved in the translocation of AZNI2 from ER-Golgi intermediate compartment (ERGIC) to the cytosol. Probably plays a key role in spermatogenesis by regulating the intracellular concentration of polyamines in haploid germ cells.
基因功能參考文獻：
1. Mutations in the OAZ3 gene are not a common cause of male infertility. PMID: 16542438
2. antizyme expression requires programmed, ribosomal frameshifting PMID: 10781085
亞細胞定位：

Nucleus. Cytoplasm.
蛋白家族：

ODC antizyme family
組織特異性：

Testis specific.
數據庫鏈接：

HGNC: 8097

OMIM: 605138

KEGG: hsa:51686

STRING: 9606.ENSP00000415904

UniGene: Hs.713789

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