NUBPL Antibody, Biotin conjugated

說明書

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) NUBPL Polyclonal antibody
Uniprot No.：

Q8TB37
基因名：

NUBPL
別名：

C14orf127 antibody; FLJ12660 antibody; huInd1 antibody; IND1 homolog antibody; Iron-sulfur protein NUBPL antibody; Nubpl antibody; NUBPL_HUMAN antibody; nucleotide binding protein like antibody; Nucleotide-binding protein-like antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human Iron-sulfur protein NUBPL protein (39-319AA)
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA
Protocols：

ELISA Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Required for the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I). May deliver of one or more Fe-S clusters to complex I subunits.
基因功能參考文獻(xiàn)：
1. huInd1 binds to the untranslated region of the TEM-1 mRNA at 3' site and thereby reducing the possibility of its endonucleolytic cleavage, resulting in over-expression of TEM-1. PMID: 25240856
2. Inhibition of ERK suppressed the NUBPL-induced changes in EMT and cell motility. PMID: 28346728
3. Our data show that NUBPL mutations are associated with a unique, consistent, and recognizable MRI pattern. PMID: 23553477
4. Mutations in NUBPL is associated with complex I deficiency. PMID: 20818383
5. These data identify huInd1 as a new assembly factor for human respiratory complex I with a possible role in the delivery of one or more Fe/S clusters to complex I subunits.[Ind1] PMID: 19752196
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相關(guān)疾病：

Mitochondrial complex I deficiency (MT-C1D)
亞細(xì)胞定位：

Mitochondrion.
蛋白家族：

Mrp/NBP35 ATP-binding proteins family
組織特異性：

Highest expression in liver and kidney. expressed at significant levels in small intestine and brain (at protein level).
數(shù)據(jù)庫鏈接：

HGNC: 20278

OMIM: 252010

KEGG: hsa:80224

STRING: 9606.ENSP00000281081

UniGene: Hs.288981

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