NSUN7 Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) NSUN7 Polyclonal antibody
Uniprot No.：

Q8NE18
基因名：

NSUN7
別名：

NSUN7Putative methyltransferase NSUN7 antibody; EC 2.1.1.- antibody; NOL1/NOP2/Sun domain family member 7 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Putative methyltransferase NSUN7 protein (1-300AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

May have S-adenosyl-L-methionine-dependent methyl-transferase activity.
基因功能參考文獻：
1. mutant protein structures of Nsun7 indicated that the amino acid serine was converted to alanine, the structure of the helix, coil and strand was changed, and the protein folding and ligand binding sites were changed in samples from asthenospermic men with a transversion mutation in exon 7, indicating impairment of protein function. Because Nsun7 plays a role in sperm motility, mutation in exon 7 may lead to infertility. PMID: 24384068
2. Our findings revealed that genetic polymorphisms in exon7 of the NSUN7 gene are not associated with asthenospermia in Chinese Han men. PMID: 26345859
3. Nsun7 (A11337)-deletion mutation, causes reduction of its protein rate and associated with sperm motility defect in infertile men. PMID: 25702163
蛋白家族：

Class I-like SAM-binding methyltransferase superfamily, RsmB/NOP family
數據庫鏈接：

HGNC: 25857

KEGG: hsa:79730

STRING: 9606.ENSP00000371201

UniGene: Hs.479602

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