NSMF Antibody
-
中文名稱：NSMF兔多克隆抗體
-
貨號：CSB-PA859576ESR2HU
-
規格：￥440
-
圖片：
-
Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA859576ESR2HU at dilution of 1:100 -
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA859576ESR2HU at dilution of 1:100
-
-
其他：
產品詳情
-
產品名稱：Rabbit anti-Homo sapiens (Human) NSMF Polyclonal antibody
-
Uniprot No.：
-
基因名：NSMF
-
別名：Nasal embryonic LHRH factor antibody; Nasal embryonic luteinizing hormone releasing hormone factor antibody; Nasal embryonic luteinizing hormone-releasing hormone factor antibody; Nelf antibody; NELF_HUMAN antibody
-
宿主：Rabbit
-
反應種屬：Human
-
免疫原：Recombinant Human NMDA receptor synaptonuclear signaling and neuronal migration factor protein (251-530AA)
-
免疫原種屬：Homo sapiens (Human)
-
標記方式：Non-conjugated
-
克隆類型：Polyclonal
-
抗體亞型：IgG
-
純化方式：Antigen Affinity Purified
-
濃度：It differs from different batches. Please contact us to confirm it.
-
保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
-
產品提供形式：Liquid
-
應用范圍：ELISA, IHC
-
推薦稀釋比：
Application Recommended Dilution IHC 1:20-1:200 -
Protocols：
-
儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
-
用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
-
功能：Couples NMDA-sensitive glutamate receptor signaling to the nucleus and triggers long-lasting changes in the cytoarchitecture of dendrites and spine synapse processes. Part of the cAMP response element-binding protein (CREB) shut-off signaling pathway. Stimulates outgrowth of olfactory axons and migration of gonadotropin-releasing hormone (GnRH) and luteinizing-hormone-releasing hormone (LHRH) neuronal cells.
-
基因功能參考文獻：
- The nuclear and non-nuclear NELF variant transcripts and proteins were identified, explaining variable NELF cellular localization. PMID: 24316376
- a model in which NELF recruits Pcf11 and NCoR1-GPS2-HDAC3 to paused RNAP II, reinforcing repression of HIV transcription and establishing a critical checkpoint for HIV transcription and latency. PMID: 23884411
- NELF is associated with normosmic idiopathic hypogonadotropic hypogonadism and Kallmann syndrome, either singly or in combination with a mutation in another gene. PMID: 21300340
- our findings implicate NELF as a nuclear protein involved in the developmental function of the reproductive axis. PMID: 20025934
- 12% of Kallman syndrome males have KAL1 deletions, but intragenic deletions of the FGFR1, GNRH1, GNRHR, GPR54 and NELF genes are uncommon in Idiopathic hypogonadotropic hypogonadism/Kallman syndrome. PMID: 18463157
顯示更多
收起更多
-
相關疾病：Hypogonadotropic hypogonadism 9 with or without anosmia (HH9)
-
亞細胞定位：Nucleus. Nucleus envelope. Nucleus membrane. Nucleus matrix. Cytoplasm. Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein. Cell projection, dendrite. Cell junction, synapse. Cell junction, synapse, synaptosome. Cell junction, synapse, postsynaptic density. Membrane.
-
蛋白家族：NSMF family
-
組織特異性：Highly expressed in adult and fetal brain. Weakly expressed in heart, liver, spleen, testis, small intestine, skeletal muscle, peripheral white blood cells and kidney.
-
數據庫鏈接：
Most popular with customers
-
YWHAB Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC, IF, FC
Species Reactivity: Human, Mouse, Rat
-
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC
Species Reactivity: Human
-
-
-
-
-
-
