NKX2-8 Antibody, FITC conjugated
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中文名稱：NKX2-8兔多克隆抗體, FITC偶聯
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貨號：CSB-PA015847LC01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) NKX2-8 Polyclonal antibody
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Uniprot No.：
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基因名：NKX2-8
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別名：Homeobox protein NK 2 homolog H antibody; Homeobox protein NK-2 homolog H antibody; Homeobox protein Nkx 2.8 antibody; Homeobox protein Nkx-2.8 antibody; NK 2 homolog 8 antibody; NK 2 homolog H antibody; NK2 homeobox 8 antibody; NK2 transcription factor related; locus 8 antibody; Nkx2 9 antibody; Nkx2-8 antibody; NKX2.8 antibody; NKX28_HUMAN antibody; NKX2G antibody; NKX2H antibody; OTTHUMP00000027959 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Homeobox protein Nkx-2.8 protein (1-160AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：FITC
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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靶點詳情
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基因功能參考文獻：
- Results show that Nkx2-8 functions as a tumor suppressor in esophageal squamous cell carcinoma (ESCC), the downregulation of which contributes to NF-kappaB P65 activation and ESCC angiogenesis. PMID: 23604637
- overexpression of Nkx2.8 resulted in downregulation of p-FOXO3a and inhibition of MEK/ERK pathway activity. silencing Nkx2.8 led to upregulation of p-FOXO3a and increase of MEK/ERK pathway activity. PMID: 22223847
- Most tumors have low expression of Nkx2-8, and its expression can inhibit growth of some lung cancer cells. PMID: 21148747
- A murine Nkx2.8 was isolated from the Hepal-6 cell line and showed oligonucleotide binding competitive with fetoprotein transcription factor. PMID: 12167706
- Coactivation of the TTF-1 and NKX2-8 pathways identified a cluster of lung cancer patients with poor survival and were shown to exhibit resistance to cisplatin PMID: 19279207
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亞細胞定位：Nucleus.
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蛋白家族：NK-2 homeobox family
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數據庫鏈接：
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