NKX2-3 Antibody, Biotin conjugated
-
中文名稱：NKX2-3兔多克隆抗體, Biotin偶聯(lián)
-
貨號(hào)：CSB-PA848391LD01HU
-
規(guī)格：￥880
-
其他：
產(chǎn)品詳情
-
產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) NKX2-3 Polyclonal antibody
-
Uniprot No.：
-
基因名：NKX2-3
-
別名：NKX2-3 antibody; NKX23 antibody; NKX2CHomeobox protein Nkx-2.3 antibody; Homeobox protein NK-2 homolog C antibody
-
宿主：Rabbit
-
反應(yīng)種屬：Human
-
免疫原：Recombinant Human Homeobox protein Nkx-2.3 protein (52-148AA)
-
免疫原種屬：Homo sapiens (Human)
-
標(biāo)記方式：Biotin
-
克隆類型：Polyclonal
-
抗體亞型：IgG
-
純化方式：>95%, Protein G purified
-
濃度：It differs from different batches. Please contact us to confirm it.
-
保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產(chǎn)品提供形式：Liquid
-
應(yīng)用范圍：ELISA
-
Protocols：
-
儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
-
用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
-
功能：Transcription factor.
-
基因功能參考文獻(xiàn)：
- Studies suggest oncogenic NK2 homeobox 3 homeobox protein (NKX2-3) in lymphomagenesis, and show a mouse model for studying the biology and therapy of human marginal-zone B-cell lymphomas. PMID: 27297662
- NKX2-3 is a key mediator for maintaining myofibroblast characteristics, and our results show that colorectal myofibroblasts, as defined by the expression of AOC3, NKX2-3, and other markers, are a distinctly different cell type from TGFbeta-activated fibroblasts PMID: 27036009
- The persons with a NKX2-3 G or T allele may have a moderately increased risk of CD. PMID: 24473197
- NKX2-3 may play different roles in ulcerative colitis and Crohn's disease pathogenesis by differential regulation of EGR1. PMID: 21968973
- A positive correlation was observed between mRNA expression of PTPN2 and NKX2-3 in B cells and in intestinal tissues from both Crohn's disease and ulcerative colitis patients. PMID: 22377701
- The binding of NFAT1 to the NKX2-3 promoter region with rs1190140 was confirmed by chromatin immunoprecipitation assay. PMID: 21803625
- the risk haplotype of NKX2.3 confers susceptibility to UC through increasing expression of NKX2.3 mRNA in the colonic mucosa. PMID: 21514341
- NKX2-3 may play an important role in inflammatory bowel disease pathogenesis by regulating endothelin-1 and VEGF signaling in human intestinal microvascular endothelial cells. PMID: 21637825
- Data suggest that NKX2-3 and IRGM are susceptibility loci for inflammatory bowel disease in Eastern European patients. PMID: 21049557
- Nkx2-3 may contribute to the pathogenesis of inflammatory bowel disease-associated colorectal cancer and sporadic colorectal cancer by regulating the Wnt signaling pathway. PMID: 20165982
- a decrease in Nkx2-3 gene expression level can profoundly alter the expression of genes and cellular functions relevant to the pathogenesis and progression of inflammatory bowel disease, such as EDN1. PMID: 20188614
- Single nucleotide polymorphism in NKX2-3 gene is associated with Crohn's disease and ulcerative colitis PMID: 18438405
- A positive association signal presumably common to different ethnic groups for rs10883365 was detected in the upstream region of NKX2-3. PMID: 18936107
顯示更多
收起更多
-
亞細(xì)胞定位：Nucleus.
-
蛋白家族：NK-2 homeobox family
-
數(shù)據(jù)庫(kù)鏈接：
Most popular with customers
-
-
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC
Species Reactivity: Human
-
-
-
-
-
-
