NKIRAS2 Antibody

中文名稱：

NKIRAS2兔多克隆抗體
貨號：

CSB-PA873696LA01HU
規(guī)格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA873696LA01HU at dilution of 1:100
其他：

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) NKIRAS2 Polyclonal antibody
Uniprot No.：

Q9NYR9
基因名：

NKIRAS2
別名：

DKFZP434N1526 antibody; I kappa B interacting Ras like protein 2 antibody; I-kappa-B-interacting Ras-like protein 2 antibody; Kappa B Ras protein 2 antibody; Kappa B-Ras protein 2 antibody; KappaB Ras2 antibody; KappaB-Ras2 antibody; KBRAS 2 antibody; KBRAS2 antibody; KBRS2_HUMAN antibody; MGC74742 antibody; NF kappa B inhibitor interacting Ras like protein 2 antibody; NF-kappa-B inhibitor-interacting Ras-like protein 2 antibody; NFKB inhibitor interacting Ras like 2 antibody; NFKB inhibitor interacting Ras like protein 2 antibody; NKIRAS 2 antibody; NKIRAS2 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human NF-kappa-B inhibitor-interacting Ras-like protein 2 protein (1-191AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產(chǎn)品，NKIRAS2 Antibody (CSB-PA873696LA01HU)，的標記方式是Non-conjugated。對于NKIRAS2 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產(chǎn)品名稱	應用
HRP	CSB-PA873696LB01HU	NKIRAS2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA873696LC01HU	NKIRAS2 Antibody, FITC conjugated
Biotin	CSB-PA873696LD01HU	NKIRAS2 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產(chǎn)品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.
基因功能參考文獻：
1. GBM cells overexpressing TNFAIP3 and NKIRAS2 were refractory to miR-125b-induced apoptosis resistance as well as TMZ resistance, indicating that both genes are relevant targets of miR-125b. PMID: 24901050
2. KappaB-Ras2 is a nuclear-cytoplasmic small GTPase that inhibits NF-kappaB activation through the suppression of transcriptional activation of p65/RelA. PMID: 20639196
亞細胞定位：

Cytoplasm.
蛋白家族：

Small GTPase superfamily, Ras family, KappaB-Ras subfamily
組織特異性：

Widely expressed.
數(shù)據(jù)庫鏈接：

HGNC: 17898

OMIM: 604497

KEGG: hsa:28511

STRING: 9606.ENSP00000303580

UniGene: Hs.632252

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