NFAM1 Antibody

中文名稱：

NFAM1兔多克隆抗體
貨號：

CSB-PA850874LA01HU
規(guī)格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA850874LA01HU at dilution of 1:100
其他：

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) NFAM1 Polyclonal antibody
Uniprot No.：

Q8NET5
基因名：

NFAM1
別名：

NFAM1 antibody; CNAIPNFAT activation molecule 1 antibody; Calcineurin/NFAT-activating ITAM-containing protein antibody; NFAT-activating protein with ITAM motif 1 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human NFAT activation molecule 1 protein (186-270AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產(chǎn)品，NFAM1 Antibody (CSB-PA850874LA01HU)，的標記方式是Non-conjugated。對于NFAM1 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產(chǎn)品名稱	應(yīng)用
HRP	CSB-PA850874LB01HU	NFAM1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA850874LC01HU	NFAM1 Antibody, FITC conjugated
Biotin	CSB-PA850874LD01HU	NFAM1 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

May function in immune system as a receptor which activates via the calcineurin/NFAT-signaling pathway the downstream cytokine gene promoters. Activates the transcription of IL-13 and TNF-alpha promoters. May be involved in the regulation of B-cell, but not T-cell, development. Overexpression activates downstream effectors without ligand binding or antibody cross-linking.
基因功能參考文獻：
1. CNAIP is a ITAM-containing protein that activates the calcineurin/NFAT-signaling pathway and the downstream cytokine gene promoters PMID: 12615919
2. Our results demonstrate NFAT expression and activation in native human vessels and point out A-285222 as a powerful pharmacological blocker of NFAT signaling in the vasculature. PMID: 17079331
3. NFAT plays a role in SV40 infection via transcriptional control of Simian Virus 40. PMID: 18031784
4. Our findings define a pathway involving CD28 binding to Grb-2 and its co-operativity with Vav1 in the regulation of T-cell co-stimulation. PMID: 18295596
亞細胞定位：

Cell membrane; Single-pass type I membrane protein.
組織特異性：

Highly expressed in neutrophils, primary monocytes, mast cells, monocytic cell lines and lymphocytes. Also expressed in spleen B and T-cells, and lung. Expressed at low level in non-immune tissue.
數(shù)據(jù)庫鏈接：

HGNC: 29872

OMIM: 608740

KEGG: hsa:150372

STRING: 9606.ENSP00000333680

UniGene: Hs.436677

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