NEUROG1 Antibody
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中文名稱：NEUROG1兔多克隆抗體
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貨號(hào)：CSB-PA100644
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規(guī)格：￥1100
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圖片：
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The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA100644(NEUROG1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200) -
Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane: Human liver cancer tissue, Primary antibody: CSB-PA100644(NEUROG1 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：
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別名：AKA antibody; Ath4c antibody; bHLHa6 antibody; Class A basic helix-loop-helix protein 6 antibody; Helix loop helix protein mATH 4C antibody; MATH4C antibody; NeuroD3 antibody; Neurog 1 antibody; Neurog1 antibody; Neurogenic basic helix loop helix protein antibody; Neurogenic basic-helix-loop-helix protein antibody; Neurogenic differentiation 3 antibody; Neurogenic differentiation factor 3 antibody; Neurogenin-1 antibody; Neurogenin1 antibody; Ngn antibody; NGN-1 antibody; Ngn1 antibody; NGN1_HUMAN antibody
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Synthetic peptide of Human NEUROG1
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：Antigen affinity purification
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,WB,IHC
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推薦稀釋比：
Application Recommended Dilution ELISA 1:1000-1:5000 WB 1:200-1:1000 IHC 1:25-1:100 -
Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Acts as a transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis.
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基因功能參考文獻(xiàn)：
- mutation not found in group of children with sensorineural hearing loss PMID: 26634621
- Results show that neurogenin-1 and -2 drive homogeneous differentiation of human stem cells into bipolar neurons in 4 days in defined media. PMID: 25403753
- We propose NEUROG1 as a new gene for syndromic autosomal recessive hearing loss and congenital cranial dysinnervation disorder PMID: 23419067
- Methylation of NEUROG1 is associated with recurrence following adjuvant FOLFOX in Stages II/III colorectal cancer. PMID: 23034738
- NEUROG1 gene is frequently found in patients, diagnosed with colorectal cancer. PMID: 21326223
- Stable expression of a single gene Ngn1 in F3 cells induces not simply neurogenic but multifunctional changes that potentially affect the differentiation of human NSC via a reorganization of complex gene regulatory networks. PMID: 19813087
- The basic helix-loop-helix region of human neurogenin 1 is a monomeric natively unfolded protein which forms a "fuzzy" complex upon DNA binding. PMID: 20102160
- Overexpression of the full-length Ngn1 induced neurite outgrowth in F11 cells in the absence of cAMP PMID: 12526089
- These results, along with a priori evidence for the involvement of neurog1 in neurodevelopment, suggest that variants in neurog1 might have a small effect on susceptibility to schizophrenia. PMID: 17044100
- Major alleles on two NEUROG1-associated SNPs (rs2344484-C-allele and rs8192558-G-allele) were significantly more prevalent among patients. this is the first study to examine brain morphological and neurocognitive correlates of NEUROG1. PMID: 18799289
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亞細(xì)胞定位：Nucleus.
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組織特異性：Expression restricted to the embryonic nervous system.
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數(shù)據(jù)庫(kù)鏈接：
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