NAPA Antibody, Biotin conjugated

說明書

中文名稱：

NAPA兔多克隆抗體, Biotin偶聯
貨號：

CSB-PA015447LD01HU
規格：

￥880
其他：

產品詳情
產品評價
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靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) NAPA Polyclonal antibody
Uniprot No.：

P54920
基因名：

NAPA
別名：

Alpha soluble NSF attachment protein antibody; Alpha-soluble NSF attachment protein antibody; N ethylmaleimide sensitive factor attachment protein alpha antibody; N-ethylmaleimide-sensitive factor attachment protein alpha antibody; napA antibody; NSF attachment protein alpha antibody; SNAA_HUMAN antibody; SNAP alpha antibody; SNAP-alpha antibody; SNAPA antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Alpha-soluble NSF attachment protein (1-295AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus (Probable). Together with GNA12 promotes CDH5 localization to plasma membrane.
基因功能參考文獻：
1. alphaSNAP is mainly expressed in the neuron brain tissue of patients with temporal lobe epilepsy. Its blood levels were significantly lower in these patients. alphaSNAP levels may increase epilepsy susceptibility. PMID: 26156199
2. data implicates beta1 integrin, FAK, and paxillin in mediating the observed pro-adhesive effects of alphaSNAP. These results reveal novel roles for alphaSNAP in regulating ECM adhesion and motility of epithelial cells. PMID: 24311785
3. Study revealed a novel role for alphaSNAP as a negative regulator of autophagy that acts by enhancing mTOR signaling and regulating the integrity of the Golgi complex. PMID: 23187805
4. novel roles for alphaSNAP in promoting the formation of epithelial adherens junctions and tight junctions by controlling golgi-dependent expression and trafficking of junctional proteins. PMID: 22485163
5. The most N-terminal part of BKV agnoprotein is involved in the interaction with alpha-SNAP PMID: 21931730
6. a novel role for alphaSNAP in promoting epithelial cell survival by unique mechanisms involving regulation of Bcl-2 expression and Golgi biogenesis PMID: 22194596
7. alpha-SNAP plays a key role in the acrosome reaction. PMID: 15542541
8. G alpha12 interaction with alphaSNAP induces VE-cadherin localization at endothelial junctions and regulates barrier function PMID: 15980433
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亞細胞定位：

Cell membrane; Peripheral membrane protein.
蛋白家族：

SNAP family
數據庫鏈接：

HGNC: 7641

OMIM: 603215

KEGG: hsa:8775

STRING: 9606.ENSP00000263354

UniGene: Hs.126938

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