NABP1 Antibody

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) NABP1 Polyclonal antibody
Uniprot No.：

Q96AH0
基因名：

NABP1
別名：

FLJ13624 antibody; FLJ22833 antibody; hSSB2 antibody; MGC111163 antibody; Nabp1 antibody; Nucleic acid-binding protein 1 antibody; OBFC2A antibody; Oligonucleotide/oligosaccharide binding fold containing 2A antibody; Oligonucleotide/oligosaccharide binding fold containing protein 2A antibody; Oligonucleotide/oligosaccharide-binding fold-containing protein 2A antibody; Sensor of single strand DNA complex subunit B2 antibody; Sensor of single-strand DNA complex subunit B2 antibody; Sensor of ssDNA subunit B2 antibody; Single stranded DNA binding protein 2 antibody; Single-stranded DNA-binding protein 2 antibody; SOSB2_HUMAN antibody; SOSS B2 antibody; SOSS complex subunit B2 antibody; SOSS-B2 antibody; SSB2 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human SOSS complex subunit B2 protein (1-204AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，NABP1 Antibody (CSB-PA850257HA01HU)，的標記方式是Non-conjugated。對于NABP1 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA850257HB01HU	NABP1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA850257HC01HU	NABP1 Antibody, FITC conjugated
Biotin	CSB-PA850257HD01HU	NABP1 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB

推薦稀釋比：

Application	Recommended Dilution
WB	1:1000-1:5000

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways.
基因功能參考文獻：
1. SNPs rs11903757, with closest proximity to NABP1 and SDPR, and rs966423 in DIRC3, were associated with survival in laryngeal squamous cell carcinoma patients. PMID: 27793000
2. hSSB1 and hSSB2 form two separate complexes with similar structures, and both complexes participate in DNA damage response. PMID: 19605351
亞細胞定位：

Nucleus. Note=Localizes to nuclear foci following DNA damage.
蛋白家族：

SOSS-B family, SOSS-B2 subfamily
數據庫鏈接：

HGNC: 26232

OMIM: 612103

KEGG: hsa:64859

STRING: 9606.ENSP00000403683

UniGene: Hs.591610

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