N Antibody, HRP conjugated

^{Rare Species}

說(shuō)明書(shū)

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Junin mammarenavirus N Polyclonal antibody
Uniprot No.：

P14239
基因名：

N
別名：

N antibody; Nucleoprotein antibody; EC 3.1.13.- antibody; Nucleocapsid protein antibody; Protein N antibody
宿主：

Rabbit
反應(yīng)種屬：

Junin mammarenavirus
免疫原：

Recombinant Junin mammarenavirus Nucleoprotein protein (1-564AA)
免疫原種屬：

Junin mammarenavirus
標(biāo)記方式：

HRP
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA
Protocols：

ELISA Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses. Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of host IRF3, a protein involved in interferon activation pathway, leading to the inhibition of interferon-beta and IRF3-dependent promoters activation. Encodes also a functional 3'-5' exoribonuclease that degrades preferentially dsRNA substrates and thereby participates in the suppression of interferon induction.
亞細(xì)胞定位：

Virion. Host cytoplasm.
蛋白家族：

Arenaviridae nucleocapsid protein family

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