MYOM1 Antibody
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中文名稱：MYOM1兔多克隆抗體
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貨號：CSB-PA015361GA01HU
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規(guī)格：￥3,900
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：MYOM1
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別名：190 kDa connectin-associated protein antibody; 190 kDa titin-associated protein antibody; EH myomesin antibody; MGC134946 antibody; MGC134947 antibody; MYOM1 antibody; MYOM1_HUMAN antibody; Myomesin (M protein) 1 (190kD) antibody; Myomesin 1 (skelemin) 185kDa antibody; Myomesin 1 185kDa antibody; Myomesin 1, 185kDa antibody; Myomesin family member 1 antibody; Myomesin-1 antibody; Skelemin antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human MYOM1-Specific
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產(chǎn)品提供形式：Liquid
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應用范圍：ELISA,WB,IHC,IF
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
相關產(chǎn)品
靶點詳情
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功能：Major component of the vertebrate myofibrillar M band. Binds myosin, titin, and light meromyosin. This binding is dose dependent.
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基因功能參考文獻：
- Crystal structure of the obscurin(-like-1):myomesin complex reveals a trans-complementation mechanism whereby an incomplete immunoglobulin-like domain assimilates an isoform-specific myomesin interdomain sequence. PMID: 27989621
- individual subfragments of titin and myomesin composed of Fn type III and Ig-like domains can activate expression of two IGF-1 splice forms in cultured myoblasts PMID: 25152160
- myomesin could act as a highly elastic ribbon to maintain the overall structural organization of the sarcomeric M-band. PMID: 22347812
- Our results suggest that the downregulation of MBNL proteins should lead to the abnormal splicing of MYOM1 exon 17a in DM1 muscle. PMID: 21794030
- EH-myomesin levels were up-regulated at least 10 times in dilated cardiomyopathy patients compared to controls. PMID: 21069531
- This missense mutation caused significant changes of biochemical and biophysical properties of myomesin fragments indicating a role in the pathogenesis of hypertrophic cardiomyopathy . PMID: 21256114
- Results identify muscle-type creatine kinase as a binding partner of a central portion of myomesin and the closely related M-protein. PMID: 12972258
- visco-elastic properties of myomesin might be crucial for the stability of the sarcomere PMID: 15890201
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亞細胞定位：Cytoplasm, myofibril, sarcomere, M line.
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數(shù)據(jù)庫鏈接：
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