MYBPC2 Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) MYBPC2 Polyclonal antibody
Uniprot No.：

Q14324
基因名：

MYBPC2
別名：

C protein, skeletal muscle fast isoform antibody; C-protein antibody; Fast MyBP C antibody; Fast MyBP-C antibody; MGC163408 antibody; MYBPC antibody; Mybpc2 antibody; MYBPCF antibody; Myosin binding protein C, fast type antibody; Myosin-binding protein C, fast-type antibody; MYPC2_HUMAN antibody; skeletal muscle fast isoform antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Myosin-binding protein C, fast-type protein (739-1141AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role.
基因功能參考文獻：
1. the mean methylation level of CpGs was significantly higher in MYBPC3 than MYBPC2. PMID: 20740642
2. The patients with a frameshift deletion mutation of MyBPC may develop LV systolic dysfunction and suffer from cardiovascular events through mid-life and beyond. PMID: 20605413
3. Identification of interactions between domains of Myosin binding protein-C that are modulated by hypertrophic cardiomyopathy missense mutations. PMID: 12386147
4. the CD-loop is a natively unfolded sequence with a likely coupling between folding and ligand binding. PMID: 17876814
5. Role and quaternary structure of MyBPC in skeletal muscle. PMID: 18201573
6. The distribution of MyBP-C in the A-bands of cardiac and skeletal muscles and compare this to the A-band structure in cardiac muscle of MyBP-C-deficient mice, was investigated. PMID: 18817784
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蛋白家族：

Immunoglobulin superfamily, MyBP family
數據庫鏈接：

HGNC: 7550

OMIM: 160793

KEGG: hsa:4606

STRING: 9606.ENSP00000350332

UniGene: Hs.85937

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