MTMR4 Antibody
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中文名稱：MTMR4兔多克隆抗體
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貨號：CSB-PA947266
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規(guī)格：￥1100
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圖片：
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The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA947266(MTMR4 Antibody) at dilution 1/15, on the right is treated with fusion protein. (Original magnification: ×200) -
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA947266(MTMR4 Antibody) at dilution 1/15, on the right is treated with fusion protein. (Original magnification: ×200)
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：
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別名：FYVE domain containing dual specificity protein phosphatase 2 antibody; FYVE domain-containing dual specificity protein phosphatase 2 antibody; FYVE domain-containing dual specificity protein phosphatase FYVE DSP2 antibody; FYVE-DSP2 antibody; Mtmr4 antibody; MTMR4_HUMAN antibody; Myotubularin related protein 4 antibody; Myotubularin-related protein 4 antibody; ZFYVE11 antibody; zinc finger FYVE domain containing 11 antibody; Zinc finger FYVE domain containing protein 11 antibody; Zinc finger FYVE domain-containing protein 11 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human,Mouse,Rat
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免疫原：Fusion protein of Human MTMR4
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：Antigen affinity purification
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,IHC
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推薦稀釋比：
Application Recommended Dilution ELISA 1:1000-1:2000 IHC 1:15-1:50 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情
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功能：Dephosphorylates proteins phosphorylated on Ser, Thr, and Tyr residues and low molecular weight phosphatase substrate para-nitrophenylphosphate. Phosphorylates phosphatidylinositol 3,4,5-trisphosphate (PIP3).
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基因功能參考文獻：
- Here the authors demonstrate that green fluorescent protein-tagged MTMR4 is recruited to the Salmonella-containing vacuole and infection of cells depleted of endogenous MTMR4 results in a decrease in viable intracellular Salmonella. PMID: 27625994
- the PH-GRAM domain of human MTMR4 was cloned, overexpressed in Escherichia coli, purified and crystallized by the vapour-diffusion method PMID: 25195910
- MTMR4 is a necessary negative modulator for the homeostasis of BMP/Dpp signaling PMID: 23150675
- MTMR4 localizes at the interface of early and recycling endosomes to regulate trafficking. PMID: 20736309
- MTMR4 belongs to the myotubularin family of phosphoinositides phosphatases PMID: 9736772
- MTMR4 plays an important role in preventing the overactivation of TGFbeta signaling by dephosphorylating activated R-Smads that have been trafficked to early endosomes PMID: 20061380
- Data found that hMTMR4 (human MTMR4) and Nedd4 co-immunoprecipitated and co-localized to late endosomes. PMID: 19125695
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亞細胞定位：Cytoplasm. Membrane; Peripheral membrane protein. Note=Localized to perinuclear region.
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蛋白家族：Protein-tyrosine phosphatase family, Non-receptor class myotubularin subfamily
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組織特異性：Expressed in brain, heart, kidney, spleen, liver, colon, testis, muscle, placenta, thyroid gland, pancreas, ovary, prostate, skin, peripheral blood, and bone marrow.
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數(shù)據(jù)庫鏈接：
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