MTIF3 Antibody

產品詳情

Uniprot No.：

Q9H2K0
基因名：

MTIF3
別名：

DC38 antibody; IF 3 antibody; IF 3Mt antibody; IF-3(Mt) antibody; IF-3Mt antibody; IF3 antibody; IF3(mt) antibody; IF3M_HUMAN antibody; IF3mt antibody; mitochondrial antibody; Mt antibody; MTIF3 antibody; Translation initiation factor IF 3; mitochondrial precursor antibody; Translation initiation factor IF-3 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Human MTIF3
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

IF-3 binds to the 28S ribosomal subunit and shifts the equilibrum between 55S ribosomes and their 39S and 28S subunits in favor of the free subunits, thus enhancing the availability of 28S subunits on which protein synthesis initiation begins.
基因功能參考文獻：
1. genetic association studies in cohorts of prediabetic patients at multiple sites: Data suggest that an SNP in MTIF3 (rs1885988) is associated with greater weight loss following lifestyle intervention in overweight/obese subjects with prediabetes. PMID: 26253612
2. single nucleotide polymorphisms rs4771122 of MTIF3 was the variant most significantly associated with long-term weight loss after surgery. PMID: 26337695
3. Changes in function or expression of MTIF3 indicates mitochondrial dysfunction and contributes to the risk of Parkinson's disease. PMID: 20887776
4. the c.798C>T polymorphism of the MTIF3 gene showed allelic association with Parkinson's disease PMID: 17267121
亞細胞定位：

Mitochondrion.
蛋白家族：

IF-3 family
數據庫鏈接：

HGNC: 29788

KEGG: hsa:219402

STRING: 9606.ENSP00000370508

UniGene: Hs.534582