MT1M Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) MT1M Polyclonal antibody
Uniprot No.：

Q8N339
基因名：

MT1M
別名：

MT1M antibody; MT1K antibody; Metallothionein-1M antibody; MT-1M antibody; Metallothionein-IM antibody; MT-IM antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Metallothionein-1M protein (1-61AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.
基因功能參考文獻：
1. Results found that MT1M is downregulated in hepatocellular carcinoma (HCC) tumors, and it suppressed HCC tumorigenesis possibly by inducing cell cycle arrest, enhancing apoptosis and inhibiting cell migration and invasion. These findings provide evidence that MT1M might be a tumor suppressor in HCC tumorigenesis. PMID: 28380433
2. Low MT1M expression is associated with poor hepatocellular carcinoma prognosis following curative resection. PMID: 27808371
3. miR-24-3p plays an important role in the initiation and progression of hepatocellular carcinoma by targeting metallothionein 1M. PMID: 27650047
4. Metallothionein MT1M is a tumor suppressor of human hepatocellular carcinomas. PMID: 22971577
蛋白家族：

Metallothionein superfamily, Type 1 family
數據庫鏈接：

HGNC: 14296

OMIM: 156357

KEGG: hsa:4499

STRING: 9606.ENSP00000369146

UniGene: Hs.647370

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