Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期:
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
May be involved in signal transduction as a component of a multimeric receptor complex.
基因功能參考文獻(xiàn):
MS4A4A is expressed at the plasma membrane in monocytes but not in granulocytes or lymphocytes. PMID: 28303902
MS4A4A expression is significantly upregulated in human masticatory mucosa during wound healing PMID: 28005267
MS4A4 in human mast cells effects ligand-induced KIT endocytosis pathways and reduced receptor recycling to the cell surface, thus promoting KIT signaling in the endosomes while reducing that in the plasma membrane. PMID: 25717186
Single nucleotide polymorphisms in APOE-epsilon4, CLU and MS4A4A influence both Alzheimer disease risk and cerebrospinal fluid Amyloid-beta1-42 levels. PMID: 23573206
亞細(xì)胞定位:
Membrane; Multi-pass membrane protein.
蛋白家族:
MS4A family
組織特異性:
Variable expression in multiple hemopoietic cell lines.