MPP7 Antibody

說明書

產品詳情

Uniprot No.：

Q5T2T1
基因名：

MPP7
別名：

FLJ32798 antibody; MAGUK p55 subfamily member 7 antibody; Membrane protein palmitoylated 7 MAGUK p55 subfamily member 7 antibody; MPP7 antibody; MPP7_HUMAN antibody; Palmitoylated membrane protein 7 antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human MPP7
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB,IHC
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Acts as an important adapter that promotes epithelial cell polarity and tight junction formation via its interaction with DLG1. Involved in the assembly of protein complexes at sites of cell-cell contact.
基因功能參考文獻：
1. MPP7 as a novel candidate gene for Primary open angle glaucoma. PMID: 27001270
2. The association of MPP7 single-nucleotide polymorphism rs4317882 gene variant with site-specific bone mineral density was determined. PMID: 22171069
3. MPP7 is a PDZ protein that interacts with human papillomavirus-16 E6 and forms a tripartite complex with LIN7A or LIN7C and DLG1, regulating the stability and localization of DLG1 to cell junctions. PMID: 17237226
4. MPP7 targets to the lateral surface of epithelial cells via its L27N domain, through an interaction with Dlg1. PMID: 17332497
亞細胞定位：

Membrane; Peripheral membrane protein. Lateral cell membrane; Peripheral membrane protein. Cell junction, tight junction. Cell junction, adherens junction. Cytoplasm, cell cortex. Cytoplasm.
蛋白家族：

MAGUK family
數據庫鏈接：

HGNC: 26542

OMIM: 610973

KEGG: hsa:143098

STRING: 9606.ENSP00000337907

UniGene: Hs.499159

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