MPP1 Antibody

中文名稱：

MPP1兔多克隆抗體
貨號：

CSB-PA014758LA01HU
規格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA014758LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA014758LA01HU at dilution of 1:100
其他：

產品詳情
產品評價
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靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) MPP1 Polyclonal antibody
Uniprot No.：

Q00013
基因名：

MPP1
別名：

55 kDa erythrocyte membrane protein antibody; AAG 12 antibody; AAG12 antibody; Aging associated gene 12 antibody; DXS552 antibody; DXS552E antibody; EM55_HUMAN antibody; EMP 55 antibody; EMP55 antibody; Erythrocyte membrane protein p55 antibody; Membrane protein antibody; Membrane protein palmitoylated 1 55kDa antibody; Membrane protein palmitoylated 1 antibody; Membrane protein; palmitoylated 1; 55kDa antibody; Migration related gene 1 antibody; MPP 1 antibody; MPP1 antibody; MRG 1 antibody; MRG1 antibody; OTTHUMP00000026054 antibody; OTTHUMP00000196176 antibody; p55 antibody; palmitoylated 1 antibody; Palmitoylated erythrocyte membrane protein antibody; Palmitoylated membrane protein 1 antibody; PEMP antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human 55 kDa erythrocyte membrane protein (123-252AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，MPP1 Antibody (CSB-PA014758LA01HU)，的標記方式是Non-conjugated。對于MPP1 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA014758LB01HU	MPP1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA014758LC01HU	MPP1 Antibody, FITC conjugated
Biotin	CSB-PA014758LD01HU	MPP1 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity.
基因功能參考文獻：
1. Data suggest that targeting the ATP binding cassette subfamily C member 4 (ABCC4)-membrane palmitoylated protein 1 (MPP1) protein complex can lead to new therapies to improve treatment outcome of acute myeloid leukemia (AML). PMID: 29146910
2. A new perspective on the role of MPP1 in erythroid cells suggests that direct MPP1-flotillins interactions could be the major driving-force behind the formation of raft domains in red blood cells. PMID: 28865798
3. conclusion, the data demonstrates that MPP1 interacts with lipid mixtures in two different model membrane systems. PMID: 28653654
4. Studies indicate that palmitoylated erythrocyte membrane protein p55 (MPP1) and its palmitoylation play a crucial role in lateral membrane organization in erythroid cells. PMID: 25408337
5. MPP1 knockdown significantly affects the activation of MAP-kinase signaling. PMID: 23507198
6. MPP1 gene expression is decreased in both classic and follicular variants of papillary thyroid carcinoma. PMID: 21509594
7. Results show the NMR-derived structure of the human erythroid p55 PDZ domain and propose a possible interaction mode with the C-terminus of glycophorin C. PMID: 16741958
8. MPP1 links the Usher protein network and the Crumbs protein complex in the retina PMID: 17584769
9. p55 binds to two distinct sites within the FERM domain, and the alternatively spliced exon 5 is necessary for the membrane targeting of protein 4.1R in epithelial cells. PMID: 18952129
10. p55-NF2 protein interaction may play a functional role in the regulation of apico-basal polarity and tumor suppression pathways in non-erythroid cells. PMID: 19144871
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亞細胞定位：

Cell membrane; Lipid-anchor. Cell projection, stereocilium.
蛋白家族：

MAGUK family
組織特異性：

Ubiquitous.
數據庫鏈接：

HGNC: 7219

OMIM: 305360

KEGG: hsa:4354

STRING: 9606.ENSP00000358547

UniGene: Hs.496984

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