MPC2 Antibody
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中文名稱：MPC2兔多克隆抗體
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貨號：CSB-PA067696
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規格：￥2024
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圖片：
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Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using BRP44 antibody.
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) MPC2 Polyclonal antibody
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Uniprot No.：
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基因名：MPC2
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別名：MPC2; BRP44; Mitochondrial pyruvate carrier 2; Brain protein 44
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宿主：Rabbit
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反應種屬：Human,Mouse
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免疫原：Synthesized peptide derived from internal of Human BRP44.
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免疫原種屬：Homo sapiens (Human)
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克隆類型：Polyclonal
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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產品提供形式：Liquid
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應用范圍：ELISA,IHC
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推薦稀釋比：
Application Recommended Dilution IHC 1:50-1:100 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Mediates the uptake of pyruvate into mitochondria.
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基因功能參考文獻：
- Hypoxia induces lactate secretion and glycolytic efflux by downregulating MPC1/MPC2 levels in HUVEC cells. PMID: 29845198
- Our study indicates that MPC1 and MPC2 expressions are of prognostic values in PCAs and that positive expression of MPC1 or MPC2 is a predictor of favorable outcome. PMID: 27852261
- a significant association between MPC2 variant rs10489202 and Schizophrenia susceptibility in Han Chinese (Meta-Analysis) PMID: 27460766
- Results indicate mitochondrial pyruvate transporter (MPC) to be the key regulatory junction perturbed by virulent strains of Mycobacterium tuberculosis leading to alteration of mitochondrial metabolic flux and regulation of acetyl-CoA formation. PMID: 28263840
- Tumor cells expressing MPC1 and MPC2 display increased mitochondrial pyruvate oxidation, with no changes in cell growth in adherent culture. PMID: 25458841
- found no significant difference (P > 0.05) in either allele or genotype frequency in the SNPs between patients and controls. PMID: 23933155
- characterization of the rat ortholog PMID: 3022128
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亞細胞定位：Mitochondrion inner membrane; Multi-pass membrane protein.
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蛋白家族：Mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family
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數據庫鏈接：
