MOBP Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) MOBP Polyclonal antibody
Uniprot No.：

Q13875
基因名：

MOBP
別名：

MOBP antibody; Myelin-associated oligodendrocyte basic protein antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Myelin-associated oligodendrocyte basic protein (1-81AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

May play a role in compacting or stabilizing the myelin sheath, possibly by binding the negatively charged acidic phospholipids of the cytoplasmic membrane.
基因功能參考文獻：
1. Mutation in MOBP gene is associated with amyotrophic lateral sclerosis. PMID: 27455348
2. rs1768208 is associated with corticobasal degeneration. PMID: 26077951
3. The rs1768208 risk polymorphism in MOBP has prognostic value in behavioral-variant frontotemporal dementia. PMID: 24994843
4. Genotypes at MOBP and EIF2AK3 confer risk predominantly in APOE epsilon4-positive subjects, with indications of an interaction between APOE and MOBP or EIF2AK3 on Alzheimer's disease risk. PMID: 23116876
5. MOBP mRNA levels were increased in the DLPFC white matter in patients with a history of substance abuse. PMID: 17964117
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亞細胞定位：

Cytoplasm, perinuclear region.
數據庫鏈接：

HGNC: 7189

OMIM: 600948

KEGG: hsa:4336

UniGene: Hs.121333

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