MIS12 Antibody
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中文名稱：MIS12兔多克隆抗體
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貨號：CSB-PA875639LA01HU
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規格：￥440
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圖片：
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Western blot
All lanes: MIS12 antibody at 2μg/ml + Hela whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 25 kDa
Observed band size: 25 kDa -
Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA875639LA01HU at dilution of 1:100 -
Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA875639LA01HU at dilution of 1:100
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) MIS12 Polyclonal antibody
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Uniprot No.：
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基因名：MIS12
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別名：MIS12 antibody; Protein MIS12 homolog antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Protein MIS12 homolog protein (1-305AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
本頁面中的產品，MIS12 Antibody (CSB-PA875639LA01HU)，的標記方式是Non-conjugated。對于MIS12 Antibody，我們還提供其他標記。見下表：
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA, WB, IHC
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:2000 IHC 1:20-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Part of the MIS12 complex which is required for normal chromosome alignment and segregation and for kinetochore formation during mitosis. Essential for proper kinetochore microtubule attachments.
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基因功能參考文獻：
- Whereas CENP-C recruits a single MIS12:NDC80 complex, the authors show here that CENP-T binds one MIS12:NDC80 and two NDC80 complexes upon phosphorylation by the mitotic CDK1:Cyclin B complex at three distinct CENP-T sites. PMID: 28012276
- RWD-containing proteins interact with the Mis12 complex to shape KMN network topology, as revealed by structural analysis PMID: 24530301
- Direct binding of Cenp-C to the Mis12 complex joins the inner and outer kinetochore. PMID: 21353556
- These findings support a novel role for Hsp90-Sgt1 chaperones in ensuring the fidelity of Mis12 multiprotein complex assembly. PMID: 20404110
- hMIS12 has a role in mitosis and localizes at kinetochores PMID: 12515822
- These results indicate that a four-subunit Mis12 complex plays an essential role in chromosome segregation in vertebrates and contributes to mitotic kinetochore assembly. PMID: 16585270
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亞細胞定位：Chromosome, centromere, kinetochore.
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蛋白家族：Mis12 family
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數據庫鏈接：
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