MGAT5B Antibody
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中文名稱：MGAT5B兔多克隆抗體
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貨號(hào)：CSB-PA013780GA01HU
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規(guī)格：￥3,900
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：MGAT5B
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別名：MGAT5B antibody; KIAA2008Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B antibody; EC 2.4.1.- antibody; EC 2.4.1.155 antibody; Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase B antibody; GlcNAc-T Vb antibody; GNT-Vb antibody; hGnTVb antibody; Mannoside acetylglucosaminyltransferase 5B antibody; N-acetylglucosaminyl-transferase Vb antibody; N-acetylglucosaminyltransferase IX antibody; GNT-IX antibody
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宿主：Rabbit
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反應(yīng)種屬：Human,Mouse,Rat
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免疫原：Human MGAT5B
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,WB
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Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Glycosyltransferase that acts on alpha-linked mannose of N-glycans and O-mannosyl glycans. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to the beta 1-6 linkage of the mannose residue of GlcNAc-beta1,2-Man-alpha on both the alpha1,3- and alpha1,6-linked mannose arms in the core structure of N-glycan. Also acts on the GlcNAc-beta1,2-Man-alpha1-Ser/Thr moiety, forming a 2,6-branched structure in brain O-mannosyl glycan. Plays an active role in modulating integrin and laminin-dependent adhesion and migration of neuronal cells via its activity in the O-mannosyl glycan pathway.
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基因功能參考文獻(xiàn)：
- we found a strong correlation between serum GnT-V activity and HDL-C concentration in human subjects PMID: 27659420
- ENPP3 is a regulator of N-acetylglucosaminyltransferase GnT-IX (GnT-Vb) PMID: 23960081
- The activity of GnT-Vb was stimulated over 4-fold in the presence of 10 mM Mn(++), and pH optimum for GnT-Vb was 8.0. PMID: 19846580
- GnT-IX is responsible for the synthesis of a unique oligosaccharide structure in the brain PMID: 12941944
- N-linked beta(1,6) branching has a role in cell-cell adhesion, cellular motility and neoplasm invasiveness PMID: 14561752
- following human GnT-IX and GnT-V transfection in COS cells, antibody specifically recognized GnT-IX, but not GnT-V, in the Golgi apparatus PMID: 16413118
- These results demonstrate that GnT-VB expression can modulate the rate of neurite outgrowth by affecting beta1 integrin-ECM interaction. PMID: 16606368
- GnT-Vb enzyme involved in the O-mannosyl glycosylation pathway, play an active role in modulating integrin and laminin-dependent adhesion and migration of human neuronal cells. PMID: 16857188
- GnT-Vb-mediated glycosylation of RPTPbeta promotes galectin-1 binding and RPTPbeta levels of retention on the cell surface. PMID: 18838383
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亞細(xì)胞定位：Golgi apparatus membrane; Single-pass type II membrane protein.
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蛋白家族：Glycosyltransferase 18 family
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組織特異性：Predominantly expressed in brain. Expressed in all area of the adult and fetal brain Also expressed at much lower level in testis, spleen and thymus.
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數(shù)據(jù)庫(kù)鏈接：
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