ME2 Antibody

中文名稱：

ME2兔多克隆抗體
貨號：

CSB-PA013633HA01HU
規格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA013633HA01HU at dilution of 1:100
其他：

產品詳情
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靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) ME2 Polyclonal antibody
Uniprot No.：

P23368
基因名：

ME2
別名：

Malate dehydrogenase antibody; Malic enzyme 2 antibody; Malic enzyme 2 mitochondrial antibody; Malic enzyme 2 NAD(+) dependent mitochondrial antibody; Malic enzyme mitochondrial antibody; Malic enzyme NAD(+) dependent mitochondrial antibody; MAOM_HUMAN antibody; ME 2 antibody; ME2 antibody; mitochondrial antibody; NAD dependent malic enzyme mitochondrial antibody; NAD ME antibody; NAD-dependent malic enzyme antibody; NAD-ME antibody; ODS1 antibody; Pyruvic malic carboxylase antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human NAD-dependent malic enzyme, mitochondrial protein (296-424AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，ME2 Antibody (CSB-PA013633HA01HU)，的標記方式是Non-conjugated。對于ME2 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA013633HB01HU	ME2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA013633HC01HU	ME2 Antibody, FITC conjugated
Biotin	CSB-PA013633HD01HU	ME2 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

基因功能參考文獻：
1. ME2 was involved in glioblastoma multiforme growth, invasion, migration, Reactive oxygen species and ATP production. PMID: 27166188
2. deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer PMID: 28099419
3. Data indicate that malic enzyme 2 knockdown impacts phosphatidylinositol 3-kinases/proto-oncogene protein akt (PI3K/AKT) signaling. PMID: 24957098
4. ME2 might be an important factor in melanoma progression and a novel biomarker of invasion. PMID: 25202825
5. Three SNP alleles in BRD2, Cx-36, and ME2 and microdeletions in 15q13.3, 15q11.2, and 16p13.11 also contribute risk to juvenile myclonic epilepsy. PMID: 23756480
6. Depletion of malic enzyme 2 induced erythroid differentiation in human erythroleukemia cells. PMID: 20824065
7. An ME2-centered nine-SNP haplotype, when present homozygously, increases the risk for IGE (odds ratio 6.1; 95% confidence interval 2.9-12.7) compared with any other genotype PMID: 15532013
8. Site directed mutagenesis was used to detrmine which amino acids in the active site of human mitochondrial NAD+-dependent malic enzyme are necessary for the inhibitory effects of ATP. PMID: 16171388
9. These findings provide a molecular rationale for the role of hS14 in TR-dependent transcriptional activation of the expression of specific genes. PMID: 17418816
10. Schizophrenic subjects are identified with mitochondrial genes involved in oxidative metabolism as showing consistently decreased expression, including ME2. PMID: 17638511
11. Single nucleotide polymorphism in ME2 gene is associated with acute lymphoblastic leukemia. PMID: 19066393
12. ME2 activity in Islets of Langerhans cells was measured by a spectrophotometric enzyme assay by utilizing the distinct kinetic properties. PMID: 19691144
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亞細胞定位：

Mitochondrion matrix.
蛋白家族：

Malic enzymes family
數據庫鏈接：

HGNC: 6984

OMIM: 154270

KEGG: hsa:4200

STRING: 9606.ENSP00000321070

UniGene: Hs.233119

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