MAPK8IP2 Antibody

說明書

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) MAPK8IP2 Polyclonal antibody
Uniprot No.：

Q13387
基因名：

MAPK8IP2
別名：

C jun amino terminal kinase interacting protein 2 antibody; C-jun-amino-terminal kinase-interacting protein 2 antibody; Homologous to mouse JIP 1 antibody; IB 2 antibody; IB-2 antibody; IB2 antibody; Islet brain 2 antibody; Islet-brain-2 antibody; JIP 2 antibody; JIP-2 antibody; JIP2 antibody; JIP2_HUMAN antibody; JNK interacting protein 2 antibody; JNK MAP kinase scaffold protein 2 antibody; JNK MAP kinase scaffold protein JIP2 antibody; JNK-interacting protein 2 antibody; MAPK8IP2 antibody; Mitogen activated protein kinase 8 interacting protein 2 antibody; Mitogen-activated protein kinase 8-interacting protein 2 antibody; PRKM8 interacting protein like antibody; PRKM8IPL antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human C-Jun-amino-terminal kinase-interacting protein 2 protein (470-570AA)
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

Non-conjugated
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA, WB

推薦稀釋比：

Application	Recommended Dilution
WB	1:1000-1:5000

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. JIP2 inhibits IL1 beta-induced apoptosis in insulin-secreting cells. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins.
基因功能參考文獻：
1. Human IB2 mutation has a role as a contributing genetic factor in chromosome 22-associated cognitive disorders. PMID: 21048139
2. there is a signaling module in which IB2 scaffolds a MLK3/MKK/p38delta kinase cascade. PMID: 12244047
亞細(xì)胞定位：

Cytoplasm.
蛋白家族：

JIP scaffold family
組織特異性：

Expressed mainly in the brain and pancreas, including insulin-secreting cells. In the nervous system, more abundantly expressed in the cerebellum, pituitary gland, occipital lobe and the amygdala. Also expressed in fetal brain. Very low levels found in ut
數(shù)據(jù)庫鏈接：

HGNC: 6883

OMIM: 607755

KEGG: hsa:23542

STRING: 9606.ENSP00000330572

UniGene: Hs.558180

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