MAP3K13 Antibody

說明書

中文名稱：

MAP3K13兔多克隆抗體
貨號：

CSB-PA003182
規格：

￥1090
圖片：
Western Blot analysis of HepG2 cells using LZK Polyclonal Antibody

Western Blot analysis of Jurkat cells using LZK Polyclonal Antibody
其他：

產品詳情

Uniprot No.：

O43283
基因名：

MAP3K13
別名：

EC 2.7.11.25 antibody; Leucine zipper bearing kinase antibody; Leucine zipper-bearing kinase antibody; LZK antibody; M3K13_HUMAN antibody; MAP3K13 antibody; MEKK13 antibody; MGC133196 antibody; Mitogen activated protein kinase kinase kinase 13 antibody; Mitogen-activated protein kinase kinase kinase 13 antibody; Mixed lineage kinase antibody; MLK antibody; OTTHUMP00000210397 antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Synthesized peptide derived from the Internal region of Human LZK.
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產品提供形式：

Liquid
應用范圍：

WB, IHC, ELISA

推薦稀釋比：

Protocols：

Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B.
基因功能參考文獻：
1. Data indicate that miR-206's effect on Myc was mediated through MAP3K13. PMID: 26918941
2. Chromosomal localization studies involving FISH mapping demonstrated that the human LZK gene is located at 3q27. PMID: 12186766
亞細胞定位：

Cytoplasm. Membrane; Peripheral membrane protein.
蛋白家族：

Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily
組織特異性：

Expressed in the adult brain, liver, placenta and pancreas, with expression strongest in the pancreas.
數據庫鏈接：

HGNC: 6852

OMIM: 604915

KEGG: hsa:9175

STRING: 9606.ENSP00000265026

UniGene: Hs.591306

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