MAGEA9 Antibody

中文名稱：

MAGEA9兔多克隆抗體
貨號：

CSB-PA013335LA01HU
規格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA013335LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA013335LA01HU at dilution of 1:100
其他：

產品詳情
產品評價
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靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) MAGEA9 Polyclonal antibody
Uniprot No.：

P43362
基因名：

MAGEA9
別名：

Cancer/testis antigen 1.9 antibody; Cancer/testis antigen family 1 member 9 antibody; CT1.9 antibody; MAGA9_HUMAN antibody; MAGE 9 antigen antibody; MAGE-9 antigen antibody; MAGE9 antibody; MAGEA9A antibody; MAGEA9B antibody; Melanoma antigen family A 9 antibody; Melanoma associated antigen 9 antibody; Melanoma-associated antigen 9 antibody; MGC8421 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Melanoma-associated antigen 9 protein (1-315AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，MAGEA9 Antibody (CSB-PA013335LA01HU)，的標記方式是Non-conjugated。對于MAGEA9 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA013335LB01HU	MAGEA9 Antibody, HRP conjugated	ELISA
FITC	CSB-PA013335LC01HU	MAGEA9 Antibody, FITC conjugated
Biotin	CSB-PA013335LD01HU	MAGEA9 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression.
基因功能參考文獻：
1. MAGE-A9 overexpression promoted cell proliferation, colony formation, migration, chemoresistance, and tumorigenicity in the context of EpCAM+ HCC cells, whereas MAGE-A9 knockdown significantly inhibited anchorage-dependent and spheroid colony formation and in vivo tumorigenicity. PMID: 29138811
2. potential X-linked candidate for the CNV67-related spermatogenic failure phenotype PMID: 28339631
3. High expression levels of MAGE-A9 are correlated with lung adenocarcinoma. PMID: 26717042
4. The results showed that the high expression of MAGE-A9 protein in NSCLC tumor cells were commonly present in squamous cell carcinomas. It was also related to larger tumor diameter, lymph node metastasis and later stage grouping with TNM classification PMID: 25755744
5. These data are the first to indicate that MAGE-A9 expression is a valuable prognostic biomarker for HCC and that high MAGE-A9 expression suggests unfavorable survival outcomes in HCC patients PMID: 25315972
6. High expression of MAGE-A9 indicates unfavorable survival outcome in laryngeal squamous cell carcinoma patients. PMID: 25400753
7. The data suggest that MAGE-A9 expression is correlated with malignant attributes of invasive ductal breast cancer PMID: 25445503
8. MAGE-A9 and MAGE-A11 are tumor-specific antigens and not only DNA hypermethylation but also histone deacetylation is responsible for the mechanism underlying MAGE-A9 and MAGE-A11 gene silencing. PMID: 24316396
9. May provide suitable targets for immunotherapy of renal cell carcinoma. PMID: 15900605
10. Overexpression of MAGE-A9 is associated with bladder cancer. PMID: 19533752
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組織特異性：

Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes and placenta.
數據庫鏈接：

HGNC: 6807

OMIM: 300342

KEGG: hsa:4108

STRING: 9606.ENSP00000298974

UniGene: Hs.460974

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