Ly6e Antibody, Biotin conjugated

說明書

中文名稱：

Ly6e兔多克隆抗體, Biotin偶聯(lián)
貨號(hào)：

CSB-PA717533LD01MO
規(guī)格：

￥880
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Mus musculus (Mouse) Ly6e Polyclonal antibody
Uniprot No.：

Q64253
基因名：

Ly6e
別名：

Ly6e antibody; Ly67 antibody; Sca-2 antibody; Tsa-1Lymphocyte antigen 6E antibody; Ly-6E antibody; Stem cell antigen 2 antibody; Thymic shared antigen 1 antibody; TSA-1 antibody
宿主：

Rabbit
反應(yīng)種屬：

Mouse
免疫原：

Recombinant Mouse Lymphocyte antigen 6E protein (21-102AA)
免疫原種屬：

Mus musculus (Mouse)
標(biāo)記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA
Protocols：

ELISA Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

GPI-anchored cell surface protein that regulates T-lymphocytes proliferation, differentiation, and activation. Regulates the T-cell receptor (TCR) signaling by interacting with component CD3Z/CD247 at the plasma membrane, leading to CD3Z/CD247 phosphorylation modulation. Restricts the entry of murine coronavirus, mouse hepatitis virus, by interfering with spike protein-mediated membrane fusion. Plays also an essential role in placenta formation by acting as the main receptor for syncytin-A (SynA). Therefore, participates in the normal fusion of syncytiotrophoblast layer I (SynT-I) and in the proper morphogenesis of both fetal and maternal vasculatures within the placenta. May also act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-3:beta-4-containing nAChRs maximum response.
基因功能參考文獻(xiàn)：
1. Knocking down Ly6e greatly reduced SynA-induced cell fusion, thus suggesting that Ly6e is the sole receptor for SynA in vivo. PMID: 28679758
2. Sca-2 -- a signal transducer situated at the nexus of surface molecules regulating death receptor-mediated apoptosis in hepatoma PMID: 15170814
亞細(xì)胞定位：

Cell membrane; Lipid-anchor, GPI-anchor.
組織特異性：

Ubiquitously expressed in mouse adult tissues with maximal expression in the lung and the salivary gland. Expression is strikingly lower in the fetal tissues except for the placenta. Present in thymus where its expression is observed in immature thymocyte
數(shù)據(jù)庫鏈接：

KEGG: mmu:17069

STRING: 10090.ENSMUSP00000056703

UniGene: Mm.788

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