LXN Antibody, Biotin conjugated
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中文名稱：LXN兔多克隆抗體, Biotin偶聯
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貨號：CSB-PA013240LD01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) LXN Polyclonal antibody
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Uniprot No.：
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基因名：LXN
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別名：ECI antibody; Endogenous carboxypeptidase inhibitor antibody; Latexin antibody; Latexin protein antibody; LXN antibody; LXN_HUMAN antibody; MUM antibody; Protein MUM antibody; TCI antibody; Tissue carboxypeptidase inhibitor antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Latexin protein (1-216AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Biotin
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA4. May play a role in inflammation.
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基因功能參考文獻：
- Results identified that LXN expression inversely modulates taxane-chemoresistance in the PC-3 prostate cancer cell line. Inhibition of LXN expression in the bone microenvironment promotes chemoresistance, in part through a methylation-dependent mechanism. PMID: 28087740
- Results show that Lxn expression was clearly decreased in the pancreatic ductal adenocarcinoma tissues suggesting it that as a tumor suppressor that targets CD133-positive cancer cells. PMID: 26530530
- Lxn protein and mRNA expression levels in CD133+ miapaca-2 cells were significantly lower than those in CD133- cells. PMID: 25551472
- latexin is markedly downregulated in hepatocellular carcinoma specimens, compared to adjacent non-cancerous tissues. PMID: 24399246
- CD146 and Lxn increased tumor migration and invasion of thyroid cancer. PMID: 23712706
- The hematopoietic stem cell regulatory gene latexin has tumor-suppressive properties in malignant melanoma. PMID: 23364479
- These results are consistent with a tumor suppressor role for latexin. PMID: 23028717
- Latexin expression is lost or greatly reduced in approximately 50% of human leukemia/lymphoma cell lines. PMID: 21567403
- downregulated expression in gastric carcinomas; tumor suppressor PMID: 21466706
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亞細胞定位：Cytoplasm.
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蛋白家族：Protease inhibitor I47 (latexin) family
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組織特異性：Highly expressed in heart, prostate, ovary, kidney, pancreas, and colon, moderate or low in other tissues including brain.
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數據庫鏈接：
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