LRRFIP1 Antibody
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中文名稱：LRRFIP1兔多克隆抗體
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貨號(hào)：CSB-PA013175HA01HU
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規(guī)格：￥440
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圖片：
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Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA013175HA01HU at dilution of 1:100 -
Immunofluorescent analysis of Hela cells using CSB-PA013175HA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) -
Immunohistochemistry of paraffin-embedded human spleen tissue using CSB-PA013175HA01HU at dilution of 1:100
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) LRRFIP1 Polyclonal antibody
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Uniprot No.：
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基因名：LRRFIP1
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別名：FLAP 1 antibody; FLAP1 antibody; FLIIAP 1 antibody; FLIIAP1 antibody; GC binding factor 2 antibody; GC-binding factor 2 antibody; GCF 2 antibody; GCF2 antibody; HUFI 1 antibody; HUFI1 antibody; Leucine rich repeat (in FLII) interacting protein 1 antibody; Leucine rich repeat flightless interacting protein 1 antibody; Leucine-rich repeat flightless-interacting protein 1 antibody; LRR FLII interacting protein 1 antibody; LRR FLII-interacting protein 1 antibody; LRRF1_HUMAN antibody; LRRFIP 1 antibody; Lrrfip1 antibody; MGC10947 antibody; MGC119738 antibody; MGC119739 antibody; NEDD8 conjugating enzyme antibody; TAR RNA interacting protein antibody; TAR RNA-interacting protein antibody; Transcription factor 9 like antibody; TRIP antibody
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Recombinant Human Leucine-rich repeat flightless-interacting protein 1 protein (1-315AA)
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：Non-conjugated
本頁(yè)面中的產(chǎn)品，LRRFIP1 Antibody (CSB-PA013175HA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于LRRFIP1 Antibody，我們還提供其他標(biāo)記。見(jiàn)下表：
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA, IHC, IF
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推薦稀釋比：
Application Recommended Dilution IHC 1:20-1:200 IF 1:50-1:200 -
Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.
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基因功能參考文獻(xiàn)：
- Results show that LRRFIP-1 is mainly produced by keratinocytes in the unwounded skin but is upregulated in both keratinocytes and fibroblasts in response to wounding, suggesting a role in the wound repair process. PMID: 29996558
- Silencing of LRRFIP1 reverses the epithelial-mesenchymal transition via inhibition of the Wnt/beta-catenin signaling pathway. PMID: 26047573
- High GCF2 expression is associated with hepatoma. PMID: 24761896
- Higher baseline LRRFIP1 expression in human glioblastoma multiforme tissue (n=60) is associated with better prognosis upon later treatment with teniposide. PMID: 24690174
- Data indicate that LRRFIP1 knockdown increased resting TNF mRNA level altered the ncRNA abundance at the LRRFIP1 binding region. PMID: 24567534
- Eight SNPs (rs7575941, rs3769053, rs11689421, rs3820808, rs11680012, rs3806505, rs6739130, and rs11686141) showed evidence of association with at least two adiposity phenotypes and plasma levels of one marker of inflammation. PMID: 23505185
- The FLI-interacting domain of LRRFIP1 forms a classic parallel, homodimeric coiled coil with 10 heptad repeats and 22 helical turns. PMID: 23099021
- GCF2/LRRFIP1 plays an important role in colorectal cancer metastasis by regulating RhoA-induced cell adhesion. PMID: 22750095
- LRRFIP1 is phosphorylated in response to immunologic stimuli and it is directed to lysosomal structures. PMID: 21102652
- An association study of 6 of the 63 genes in 4235 cases and 6379 controls showed a putative association with myocardial infarction for COMMD7 (COMM domain-containing protein 7) and a major deviation from the null hypo thesis for LRRFIP1. PMID: 20833976
- GCF2/LRRFIP1 appears to act as a repressor and occupies the -308 site in cells that do not make TNF-alpha. PMID: 16199883
- Immediately following lipopolysaccharide stimulation, both LRRFIP2 and Flap-1/LRRFIP1 compete with Fliih for interacting with MyD88 to activate the signaling. PMID: 19265123
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亞細(xì)胞定位：Nucleus. Cytoplasm.
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蛋白家族：LRRFIP family
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組織特異性：Ubiquitously expressed.
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數(shù)據(jù)庫(kù)鏈接：
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