LCMT1 Antibody
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中文名稱：LCMT1兔多克隆抗體
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貨號：CSB-PA523947
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規格：￥1100
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圖片：
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The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA523947(LCMT1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200) -
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA523947(LCMT1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200) -
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: 231 cells, Primary antibody: CSB-PA523947(LCMT1 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
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其他：
產品詳情
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Uniprot No.：
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基因名：LCMT1
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別名：[Phosphatase 2A protein]-leucine-carboxy methyltransferase 1 antibody; CGI 68 antibody; LCMT antibody; LCMT1 antibody; LCMT1_HUMAN antibody; Leucine carboxyl methyltransferase 1 antibody; PPMT1 antibody; Protein leucine O methyltransferase antibody; protein phosphatase methyltransferase 1 antibody; Protein-leucine O-methyltransferase antibody
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宿主：Rabbit
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反應種屬：Human,Rat
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免疫原：Fusion protein of Human LCMT1
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：Antigen affinity purification
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產品提供形式：Liquid
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應用范圍：ELISA,WB,IHC
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推薦稀釋比：
Application Recommended Dilution ELISA 1:1000-1:2000 WB 1:200-1:1000 IHC 1:25-1:100 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
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靶點詳情
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功能：Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.
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基因功能參考文獻：
- alterations in the membrane localization of PP2A and Tau following down-regulation of LCMT1 may lead to PP2A and Tau dysfunction in AD. PMID: 23943618
- determined crystal structures of human LCMT-1 in isolation and in complex with PP2A stabilized by a cofactor mimic. The structures show that the LCMT-1 active-site pocket recognizes the carboxyl terminus of PP2A PMID: 21292165
- X-ray crystal structure of human LCMT1 protein in complex with the cofactor S-adenosylmethionine (AdoMet) has been solved to a resolution of 2 A. PMID: 21206058
- LCMT-1 is important for normal progression through mitosis and cell survival and is essential for embryonic development PMID: 17724024
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蛋白家族：Methyltransferase superfamily, LCMT family
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數據庫鏈接：
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