L2 Antibody

Name: L2 Antibody
Brand: CUSABIO
SKU: CSB-PA356939LA01HMN

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說明書

產品詳情

產品名稱：

Rabbit anti-Human papillomavirus type 18 L2 Polyclonal antibody
Uniprot No.：

P06793
基因名：

L2
別名：

L2 antibody; Minor capsid protein L2 antibody
宿主：

Rabbit
反應種屬：

Human papillomavirus type 18
免疫原：

Recombinant Human papillomavirus type 18 Minor capsid protein L2 protein (1-462AA)
免疫原種屬：

Human papillomavirus type 18

標記方式：

Non-conjugated

本頁面中的產品，L2 Antibody (CSB-PA356939LA01HMN)，的標記方式是Non-conjugated。對于L2 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA356939LB01HMN	L2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA356939LC01HMN	L2 Antibody, FITC conjugated
Biotin	CSB-PA356939LD01HMN	L2 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Minor protein of the capsid that localizes along the inner surface of the virion, within the central cavities beneath the L1 pentamers. Plays a role in capsid stabilization through interaction with the major capsid protein L1. Once the virion enters the host cell, L2 escorts the genomic DNA into the nucleus by promoting escape from the endosomal compartments and traffic through the host Golgi network. Mechanistically, the C-terminus of L2 possesses a cell-penetrating peptide that protudes from the host endosome, interacts with host cytoplasmic retromer cargo and thereby mediates the capsid delivery to the host trans-Golgi network. Plays a role through its interaction with host dynein in the intracellular microtubule-dependent transport of viral capsid toward the nucleus. Mediates the viral genome import into the nucleus through binding to host importins. Once within the nucleus, L2 localizes viral genomes to host PML bodies in order to activate early gene expression for establishment of infection. Later on, promotes late gene expression by interacting with the viral E2 protein and by inhibiting its transcriptional activation functions. During virion assembly, encapsidates the genome by direct interaction with the viral DNA.
亞細胞定位：

Virion. Host nucleus. Host early endosome. Host Golgi apparatus.
蛋白家族：

Papillomaviridae L2 protein family
數據庫鏈接：

KEGG: vg:1489091

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