KYNU Antibody
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中文名稱：KYNU兔多克隆抗體
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貨號：CSB-PA621970ESR1HU
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規格：￥440
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圖片：
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Western blot
All lanes: KYNU antibody at 3.26μg/ml
Lane 1: A549 whole cell lysate
Lane 2: HepG2 whole cell lysate
Lane 3: THP-1 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 53, 35 kDa
Observed band size: 53 kDa -
Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA621970ESR1HU at dilution of 1:100 -
Immunoprecipitating KYNU in Hela whole cell lysate
Lane 1: Rabbit control IgG instead of (1μg) instead of CSB-PA621970ESR1HU in Hela whole cell lysate. For western blotting, a HRP-conjugated anti-rabbit IgG, specific to the non-reduced form of IgG was used as the Secondary antibody (1/50000)
Lane 2: CSB-PA621970ESR1HU (4μg) + Hela whole cell lysate (500μg)
Lane 3: Hela whole cell lysate (20μg)
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) KYNU Polyclonal antibody
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Uniprot No.：
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基因名：KYNU
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別名：kynU antibody; KYNU_HUMAN antibody; kynureninase (L-kynurenine hydrolase) antibody; Kynureninase antibody; L-kynurenine hydrolase antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Kynureninase protein (1-307AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產品提供形式：Liquid
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應用范圍：ELISA, WB, IHC, IP
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推薦稀釋比：
Application Recommended Dilution WB 1:1000-1:5000 IHC 1:20-1:200 IP 1:200-1:2000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity.
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基因功能參考文獻：
- Our results suggest that tryptophan metabolism might dichotomously modulate immune responses, with KYNU as a switch between immunosuppressive versus inflammatory outcomes. PMID: 26725996
- A rare variant at the KYNU gene is associated with essential hypertension in the Han Chinese population. PMID: 22012986
- The Lys412Glu polymorphism of the KYNU gene in a hypertensive candidate chromosomal region is associated with essential hypertension in Han Chinese. PMID: 16080802
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相關疾病：Hydroxykynureninuria (HYXKY); Vertebral, cardiac, renal, and limb defects syndrome 2 (VCRL2)
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亞細胞定位：Cytoplasm, cytosol.
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蛋白家族：Kynureninase family
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組織特異性：Expressed in all tissues tested (heart, brain placenta, lung, liver, skeletal muscle, kidney and pancreas). Highest levels found in placenta, liver and lung. Expressed in all brain regions.
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數據庫鏈接：
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