KLRC3 Antibody

中文名稱：

KLRC3兔多克隆抗體
貨號：

CSB-PA23099A0Rb
規(guī)格：

￥440
圖片：
IHC image of CSB-PA23099A0Rb diluted at 1:400 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Immunofluorescence staining of Hela cells with CSB-PA23099A0Rb at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
其他：

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) KLRC3 Polyclonal antibody
Uniprot No.：

Q07444
基因名：

KLRC3
別名：

Killer cell lectin like receptor subfamily C member 3 antibody; KLRC 3 antibody; KLRC3 antibody; NK cell receptor E antibody; NKG2 E activating NK receptor antibody; NKG2 E antibody; NKG2 E type II integral membrane protein antibody; NKG2-E type II integral membrane protein antibody; NKG2-E-activating NK receptor antibody; NKG2E activating NK receptor antibody; NKG2E antibody; NKG2E type II integral membrane protein antibody; NKG2E_HUMAN antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human NKG2-E type II integral membrane protein (94-240AA)
免疫原種屬：

Homo sapiens (Human)

標(biāo)記方式：

Non-conjugated

本頁面中的產(chǎn)品，KLRC3 Antibody (CSB-PA23099A0Rb)，的標(biāo)記方式是Non-conjugated。對于KLRC3 Antibody，我們還提供其他標(biāo)記。見下表：

標(biāo)記方式	貨號	產(chǎn)品名稱	應(yīng)用
HRP	CSB-PA23099B0Rb	KLRC3 Antibody, HRP conjugated	ELISA
FITC	CSB-PA23099C0Rb	KLRC3 Antibody, FITC conjugated
Biotin	CSB-PA23099D0Rb	KLRC3 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA, IHC, IF

推薦稀釋比：

Application	Recommended Dilution
IHC	1:200-1:500
IF	1:50-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.
基因功能參考文獻(xiàn)：
1. KLRC3 gene expression is linked to glioblastoma aggressiveness. PMID: 27641066
2. Data indicate that NKG2 receptor NKG2E was capable of associating with CD94 and DAP12 but that the complex was retained intracellularly at the endoplasmic reticulum. PMID: 24935923
3. Data indicate that the expression of KLRD1 (CD94) and NKG2E (KLRC3) was reduced in NK-enriched cells in fulminant type 1 diabetes. PMID: 24177169
亞細(xì)胞定位：

Membrane; Single-pass type II membrane protein.
組織特異性：

Natural killer cells.
數(shù)據(jù)庫鏈接：

HGNC: 6376

OMIM: 602892

KEGG: hsa:3823

STRING: 9606.ENSP00000437563

UniGene: Hs.654362

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