KIR2DS3 Antibody, FITC conjugated
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中文名稱：KIR2DS3兔多克隆抗體, FITC偶聯
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貨號：CSB-PA613530LC01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) KIR2DS3 Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：KIR2DS3 antibody; NKAT7Killer cell immunoglobulin-like receptor 2DS3 antibody; MHC class I NK cell receptor antibody; Natural killer-associated transcript 7 antibody; NKAT-7 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Killer cell immunoglobulin-like receptor 2DS3 protein (102-241AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：FITC
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
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靶點詳情
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功能：Receptor on natural killer (NK) cells for HLA-C alleles. Does not inhibit the activity of NK cells.
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基因功能參考文獻：
- activating KIR2DS3 was associated with rapid leukocyte engraftment after hematopoietic stem cell transplantation from matched sibling PMID: 28993188
- Genotypes missing these two inhibitory KIR-HLA combinations in addition to missing activating KIRs 2DS2 and 2DS3 were more common in Vogt-Koyanagi-Harada disease (OR = 1.90, P = 0.002). PMID: 27490240
- Loss of KIR2DS3 gene is associated with breast cancer. PMID: 27631728
- genetic polymorphism is associated with childhood acute lymphoblastic leukemia among north Indians PMID: 26472014
- The genes KIR2DL5, KIR2DS3 and KIR2DS5 were present in a significantly higher proportion of individuals in the asymptomatic control group than in the malaria cases. PMID: 24929143
- the presence of host genetic risk factors, IL28B-T and KIR2DS3 alleles, resulted in increased odds of treatment failure in these rapid virological response negative patients. PMID: 23826153
- KIR2DS3 and HLA-class I alleles (-Cw*14 and -Cw*17) may play a role in the pathogenesis of the Vogt-Koyanagi-Harada disease. PMID: 22219647
- The Natural Killer cell gene KIR2DS3 was significantly increased in patients with chronic hepatitis C virus infection. PMID: 21402922
- KIR2DS3 is associated with protection against acute myeloid leukemia. PMID: 20371915
- Positive linkage disequilibrium was seen between KRI2DS2 and KIR2DS3. Positive linkage disequilibrium was seen between KIR3DS1 and KIR2DS3. PMID: 12559621
- KIR2DS3 is a protective factor for chronic graft-versus-host disease. PMID: 17462498
- This focuses on the inheritance of KIR2DS3*001 and *002 to clarify their genetic relationship, and will investigate the diversity of haplotypes containing a KIR2DS3 gene. PMID: 18480828
- Genomic and mRNA sequences support the KIR2DS3*002 gene being a hybrid of KIR2DS3*00103 and KIR2DS5. PMID: 18764809
- Dramatically reduced surface expression of NK cell receptor KIR2DS3 is attributed to multiple residues throughout the molecule. PMID: 19005473
- KIR2DS3 incompatibilities increased risk of chronic graft-versus-host disease after allogeneic hematopoietic stem cell transplantation PMID: 19500138
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亞細胞定位：Cell membrane; Single-pass type I membrane protein.
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蛋白家族：Immunoglobulin superfamily
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數據庫鏈接：
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