KIF26B Antibody

說明書

產品詳情

Uniprot No.：

Q2KJY2
基因名：

KIF26B
別名：

FLJ10157 antibody; KI26B_HUMAN antibody; KIF26B antibody; Kinesin-like protein KIF26B antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human KIF26B
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,IHC
Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Essential for embryonic kidney development. Plays an important role in the compact adhesion between mesenchymal cells adjacent to the ureteric buds, possibly by interacting with MYH10. This could lead to the establishment of the basolateral integrity of the mesenchyme and the polarized expression of ITGA8, which maintains the GDNF expression required for further ureteric bud attraction. Although it seems to lack ATPase activity it is constitutively associated with microtubules.
基因功能參考文獻：
1. Upregulation of KIF26B enhanced proliferation and migration of ovarian cancer cells in vitro PMID: 29880787
2. KIF26B, a novel oncogene regulated by miR-372, promotes proliferation and metastasis through the VEGF pathway in gastric cancer PMID: 28581513
3. KIF26B plays an important role in colorectal carcinogenesis and functions as a novel prognostic indicator and a potential therapeutic target for CRC. PMID: 25652119
4. High expression of KIF26B in breast cancer associates with poor prognosis. PMID: 23585914
亞細胞定位：

Cytoplasm. Cytoplasm, cytoskeleton.
蛋白家族：

TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family, KIF26 subfamily
數據庫鏈接：

HGNC: 25484

OMIM: 614026

KEGG: hsa:55083

STRING: 9606.ENSP00000385545

UniGene: Hs.143134

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