KCNH7 Antibody

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) KCNH7 Polyclonal antibody
Uniprot No.：

Q9NS40
基因名：

KCNH7
別名：

KCNH7 antibody; ERG3Potassium voltage-gated channel subfamily H member 7 antibody; Ether-a-go-go-related gene potassium channel 3 antibody; ERG-3 antibody; Eag-related protein 3 antibody; Ether-a-go-go-related protein 3 antibody; hERG-3 antibody; Voltage-gated potassium channel subunit Kv11.3 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Potassium voltage-gated channel subfamily H member 7 protein (1-300AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產(chǎn)品，KCNH7 Antibody (CSB-PA878877LA01HU)，的標記方式是Non-conjugated。對于KCNH7 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產(chǎn)品名稱	應用
HRP	CSB-PA878877LB01HU	KCNH7 Antibody, HRP conjugated	ELISA
FITC	CSB-PA878877LC01HU	KCNH7 Antibody, FITC conjugated
Biotin	CSB-PA878877LD01HU	KCNH7 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產(chǎn)品提供形式：

Liquid
應用范圍：

ELISA, IHC, IF

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Pore-forming (alpha) subunit of voltage-gated potassium channel. Channel properties may be modulated by cAMP and subunit assembly.
基因功能參考文獻：
1. we have discovered that, the Kv11.3 (hERG3) a plasma-membrane potassium channel plays a critical role in the regulation of autophagy in a melanoma cell model PMID: 26942884
2. KCNH7 c.1181G>A had the highest enrichment among individuals with bipolar spectrum disorder (x2 5 7.3) and the strongest family-based association with bipolar 1 (P 5 0.021), bipolar spectrum (P 5 0.031) and any major affective disorder (P 5 0.016). PMID: 24986916
3. The recombinant wild-type ERG3 protein produced in HEK cells generates two prominent bands. When the entire CNBD of ERG3 protein was deleted, only an EndoH-sensitive band was generated, indicating that this band constitutes the immature species. PMID: 15961404
亞細胞定位：

Membrane; Multi-pass membrane protein.
蛋白家族：

Potassium channel family, H (Eag) (TC 1.A.1.20) subfamily, Kv11.3/KCNH7 sub-subfamily
組織特異性：

Expressed in prolactin-secreting adenomas.
數(shù)據(jù)庫鏈接：

HGNC: 18863

OMIM: 608169

KEGG: hsa:90134

STRING: 9606.ENSP00000331727

UniGene: Hs.657413

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