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KCNH3 Antibody

說明書

中文名稱：

KCNH3兔多克隆抗體
貨號：

CSB-PA593481
規格：

￥1100
圖片：
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA593481(KCNH3 Antibody) at dilution 1/12, on the right is treated with synthetic peptide. (Original magnification: ×200)
其他：

產品詳情

Uniprot No.：

Q9ULD8
基因名：

KCNH3
別名：

KCNH3 antibody; KIAA1282Potassium voltage-gated channel subfamily H member 3 antibody; Brain-specific eag-like channel 1 antibody; BEC1 antibody; Ether-a-go-go-like potassium channel 2 antibody; ELK channel 2 antibody; ELK2 antibody; Voltage-gated potassium channel subunit Kv12.2 antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Synthetic peptide of Human KCNH3
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

Antigen affinity purification
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
產品提供形式：

Liquid
應用范圍：

ELISA,IHC

推薦稀釋比：

Application	Recommended Dilution
ELISA	1:1000-1:2000
IHC	1:10-1:50

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits an outward current with fast inactivation. Channel properties may be modulated by cAMP and subunit assembly.
基因功能參考文獻：
1. report on the binding of HIV-1 gp120 to the cytoplasmic C-terminus of the voltage-gated potassium channel BEC1, an interaction that can result in the repression of BEC's activity and the inhibition of HIV-1 particle-release PMID: 20638388
2. BEC1 is negatively involved in cognitive functions with no abnormal behaviors such as spontaneous seizures or motor dysfunction. PMID: 19923296
亞細胞定位：

Membrane; Multi-pass membrane protein.
蛋白家族：

Potassium channel family, H (Eag) (TC 1.A.1.20) subfamily, Kv12.2/KCNH3 sub-subfamily
組織特異性：

Detected only in brain, in particular in the telencephalon. Detected in the cerebral cortex, occipital pole, frontal and temporal lobe, putamen, amygdala, hippocampus and caudate nucleus.
數據庫鏈接：

HGNC: 6252

OMIM: 604527

KEGG: hsa:23416

STRING: 9606.ENSP00000257981

UniGene: Hs.64064

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