ISCA2 Antibody, HRP conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) ISCA2 Polyclonal antibody
Uniprot No.：

Q86U28
基因名：

ISCA2
別名：

c14_5557 antibody; HESB like domain containing 1 antibody; HESB like domain containing protein 1 antibody; HESB-like domain-containing protein 1 antibody; iron sulfur cluster assembly 2 homolog (S. cerevisiae) antibody; Iron sulfur cluster assembly 2 homolog; mitochondrial antibody; Iron-sulfur cluster assembly 2 homolog; mitochondrial antibody; ISCA2 antibody; ISCA2_HUMAN antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Iron-sulfur cluster assembly 2 homolog, mitochondrial protein (9-154AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

HRP
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway. May be involved in the binding of an intermediate of Fe/S cluster assembly.
基因功能參考文獻：
1. We identified a homoallelic missense founder mutation in ISCA2 leading to mitochondrial depletion and reduced complex I activity as well as decreased ISCA2, ISCA1 and IBA57 expression in fibroblasts. PMID: 25539947
相關疾病：

Multiple mitochondrial dysfunctions syndrome 4 (MMDS4)
亞細胞定位：

Mitochondrion.
蛋白家族：

HesB/IscA family
數據庫鏈接：

HGNC: 19857

OMIM: 615317

KEGG: hsa:122961

STRING: 9606.ENSP00000452007

UniGene: Hs.291079

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