IL20RB Antibody

產(chǎn)品詳情

Uniprot No.：

Q6UXL0
基因名：

IL20RB
別名：

DIRS1 antibody; Fibronectin type III domain containing 6 antibody; FNDC6 antibody; I20RB_HUMAN antibody; IL 20R beta antibody; IL 20R2 antibody; IL-20 receptor subunit beta antibody; IL-20R-beta antibody; IL-20R2 antibody; IL-20RB antibody; IL20RB antibody; Interleukin 20 receptor beta antibody; Interleukin 20 receptor beta chain precursor antibody; Interleukin 20 receptor II antibody; Interleukin-20 receptor subunit beta antibody; MGC34923 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Human IL20RB
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,WB,IF
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunofluorescence (IF) Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL22RA1/IL20RB dimer is a receptor for IL20 and IL24.
基因功能參考文獻(xiàn)：
1. Trabecular meshwork cells express IL-20 receptors; Mutation of the T104 residue in IL-20R2 leads to a reduction in STAT3 phosphorylation as well as decreased matrix metalloproteinase activity PMID: 24455976
2. The crystal structure of the IL-20/IL-20R1/IL-20R2 complex reveals how type I and II complexes discriminate cognate from noncognate ligands PMID: 22802649
3. The hypotheses that genetic variations of the IL-20-RI influence susceptibility to psoriasis and single nucleotide polymorphisms (SNPs) in the IL20RA and IL20RB genes in psoriasis patients were investigated. PMID: 18480827
亞細(xì)胞定位：

Membrane; Single-pass type I membrane protein.
蛋白家族：

Type II cytokine receptor family
組織特異性：

Widely expressed with highest levels in skin and testis. Highly expressed in psoriatic skin.
數(shù)據(jù)庫(kù)鏈接：

HGNC: 6004

OMIM: 605621

KEGG: hsa:53833

STRING: 9606.ENSP00000328133

UniGene: Hs.61232