IGSF11 Antibody

說明書

產品詳情

Uniprot No.：

Q5DX21
基因名：

IGSF11
別名：

IGSF11 antibody; BTIGSF antibody; CXADRL1 antibody; VSIG3 antibody; Immunoglobulin superfamily member 11 antibody; IgSF11 antibody; Brain and testis-specific immunoglobulin superfamily protein antibody; Bt-IGSF antibody; V-set and immunoglobulin domain-containing protein 3 antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human IGSF11
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB,IHC
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Functions as a cell adhesion molecule through homophilic interaction. Stimulates cell growth.
基因功能參考文獻：
1. Concerted role for IgSF11 and PSD-95 in the regulation of AMPAR-mediated synaptic transmission and plasticity. PMID: 26595655
2. Molecular cloning of BT-IgSF which is preferentially expressed by brain and testis PMID: 12207903
3. cell adhesion-inducing function of BT-IgSF suggests a role of the cell surface molecule in the development/function of the central nervous system and spermatogenesis PMID: 15795899
4. IGSF11 is a good candidate of cancer-testis antigen. Furthermore, suppression of IGSF11 by siRNA retarded the growth of gastric cancer cells. PMID: 16108831
亞細胞定位：

Cell membrane; Single-pass type I membrane protein.
組織特異性：

Abundantly expressed in testis and ovary and to a lower extent in brain, kidney and skeletal muscle.
數據庫鏈接：

HGNC: 16669

OMIM: 608351

KEGG: hsa:152404

STRING: 9606.ENSP00000377370

UniGene: Hs.112873

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