HS3ST1 Antibody, FITC conjugated
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中文名稱：HS3ST1兔多克隆抗體, FITC偶聯
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貨號：CSB-PA010747LC01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) HS3ST1 Polyclonal antibody
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Uniprot No.：
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基因名：HS3ST1
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別名：3-OST-1 antibody; 3OST antibody; 3OST1 antibody; EC 2.8.2.23 antibody; h3 OST 1 antibody; h3-OST-1 antibody; Heparan sulfate (glucosamine) 3 O sulfotransferase 1 antibody; Heparan sulfate 3 O sulfotransferase 1 antibody; Heparan sulfate 3-O-sulfotransferase 1 antibody; Heparan sulfate D glucosaminyl 3 O sulfotransferase 1 antibody; Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1 antibody; Heparan sulfate glucosamine 3-O-sulfotransferase 1 antibody; Heparin glucosamine 3 O sulfotransferase antibody; HS3S1_HUMAN antibody; HS3ST 1 antibody; Hs3st1 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Heparan sulfate glucosamine 3-O-sulfotransferase 1 protein (21-307AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：FITC
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
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靶點詳情
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功能：Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to position 3 of glucosamine residues in heparan. Catalyzes the rate limiting step in the biosynthesis of heparan sulfate (HSact). This modification is a crucial step in the biosynthesis of anticoagulant heparan sulfate as it completes the structure of the antithrombin pentasaccharide binding site.
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基因功能參考文獻：
- Compared with Hs3st1+/+ mice, Hs3st1-/- mice were more susceptible to LPS-induced death due to an increased sensitivity to TNF PMID: 28126521
- Golgi-targeted HS3st1 localizes in the Golgi and results in the formation of a single type of AT-binding site and high anti-factor Xa activity PMID: 24247246
- In this paper a conformational change is described that occurs in heparan sulfate 3-O-sulfotransferase-1 upon binding to heparan sulfate. PMID: 15096036
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亞細胞定位：Golgi apparatus lumen.
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蛋白家族：Sulfotransferase 1 family
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組織特異性：Highly expressed in the brain and kidney and weakly expressed in the heart, lung and placenta.
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數據庫鏈接：
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